Corti Marcelo E, Villafañe María F, Suárez Anzorena Francisco, Daruich Jorge, Pérez Bianco Raúl, Candela Miguel, Ferraina Pedro, Tezanos Pinto Miguel
Hospital de Clínicas José de San Martín, Facultad de Medicina, Universidad de Buenos Aires.
Medicina (B Aires). 2003;63(3):224-6.
Thrombocytopenia is an important and common hematological abnormality in patients with HIV-1/HCV coinfection. Splenomegaly is a frequent finding in these patients and usually causes hypersplenism and thrombocytopenia. We analyzed the clinical results of a minimal invasive treatment (splenic artery embolization) for thrombocytopenia secondary to hypersplenism and refractory to other therapies in two hemophiliac patients, HIV seropositive and with cirrhosis due to chronic HCV infection. The results suggest that splenic artery embolization is a safe, relatively atraumatic and effective method for the treatment of splenomegaly and hypersplenism in selected patients with HIV-1/HCV coinfection.
血小板减少症是HIV-1/HCV合并感染患者重要且常见的血液学异常。脾肿大在这些患者中很常见，通常会导致脾功能亢进和血小板减少症。我们分析了两名血友病患者（HIV血清阳性，因慢性丙型肝炎病毒感染导致肝硬化）因脾功能亢进继发血小板减少症且对其他治疗无效时采用微创治疗（脾动脉栓塞术）的临床结果。结果表明，脾动脉栓塞术是治疗部分HIV-1/HCV合并感染患者脾肿大和脾功能亢进的一种安全、相对无创且有效的方法。
