Locard E, Mamelle N, Munoz F, Miginiac M, Billette A, Rey S
GREPS, Groupe de Recherche en Education Pour la Santé, Lyon, France.
Rev Epidemiol Sante Publique. 1992;40(6):460-6.
The increasing level of childhood obesity has prompted some research into the early risk factors likely to lead to preventive measures. A case-control study was conducted of a five year-old population in the Rhône and Isère administrative "départements" of France during the children's first visit to primary school, with the participation of 327 obese children and 704 controls. Anthropometric data on the children since birth, together with data on their lifestyles, were collected in interviews with parents. "Family obesity" and "obesity at birth" were found to be closely related to the child's obesity at five years old (adjusted OR = 2.7 and 2.1 respectively). Of the environmental factors, the hypothesis tested paid specific attention to television viewing, snacks between meals and lack of sleep. These three variables were all found to be risk factors of obesity at five years old. However after allowing for parental obesity, the only remaining significant risk factor for obesity at five was lack of sleep (adjusted OR = 1.4). The pathogenic assumptions raised by these results are discussed.
儿童肥胖率的不断上升促使人们对可能导致预防措施的早期风险因素展开了一些研究。在法国罗纳省和伊泽尔省行政区，针对五岁儿童开展了一项病例对照研究，这些儿童首次进入小学时参与研究，其中有327名肥胖儿童和704名对照儿童。通过与家长访谈，收集了这些儿童自出生以来的人体测量数据以及他们的生活方式数据。研究发现，“家族肥胖”和“出生时肥胖”与儿童五岁时的肥胖密切相关（调整后的比值比分别为2.7和2.1）。在环境因素方面，所检验的假设特别关注看电视、两餐之间吃零食和睡眠不足。这三个变量均被发现是五岁时肥胖的风险因素。然而，在考虑到父母肥胖因素后，五岁时肥胖唯一剩下的显著风险因素是睡眠不足（调整后的比值比 = 1.4）。本文对这些结果所引发的致病假设进行了讨论。
