Szaflarska-Szczepanik Anna, Gasiorowska Joanna
Katedra i Klinika Pediatrii, Alergologii i Gastroenterologii, Akademia Medyczna, ul. M. Skłodowskiej-Curie 9, 85-094 Bydgoszcz, Poland.
Med Wieku Rozwoj. 2003 Apr-Jun;7(2):241-8.
Because of contradictory data about the prevalence of soya allergy in children recommendations for the use of the protein-based formulas are ambiguous. THE AIM of the study was to estimate the prevalence of soya allergy in children with IgE-associated cow's milk allergy.
Ninety seven patients aged from six months to four years with personal history suggestive of food allergy with specific IgE to cow's milk protein attending the Department of Pediatrics, Allergology and Gastroenterology between 2000-2002 were studied. In all patients specific IgE to soya protein were detected.
In 45% children with IgE-associated cow's milk allergy specific IgE to soya protein were detected. Clinical manifestation in both groups of children with or without specific IgE to soya protein was similar. Gastrointestinal tract symptoms were observed more often in children with cow's milk and soya allergy than in children with cow's milk allergy (52 and 42% respectively) and atopic dermatitis was observed more often in children with cow's milk allergy than in children with cow's milk and soya allergy (81 and 74% respectively). The incidence of respiratory tract symptoms in both groups of children was similar. The differences were not statistically significant.
It seems, that hydrolyzed formulas should be the preferred choice for children because of a high prevalence of soya protein allergy in children with IgE- associated cow's milk allergy.
由于关于儿童大豆过敏患病率的数据相互矛盾,基于蛋白质配方奶粉的使用建议并不明确。本研究的目的是评估与IgE相关的牛奶过敏儿童中大豆过敏的患病率。
对2000年至2002年间在儿科、过敏科和胃肠病科就诊的97名年龄在6个月至4岁之间、有食物过敏个人史且对牛奶蛋白有特异性IgE的患者进行了研究。对所有患者均检测了对大豆蛋白的特异性IgE。
在与IgE相关的牛奶过敏儿童中,45%检测到对大豆蛋白的特异性IgE。有或没有对大豆蛋白特异性IgE的两组儿童的临床表现相似。牛奶和大豆过敏儿童的胃肠道症状比牛奶过敏儿童更常见(分别为52%和42%),牛奶过敏儿童的特应性皮炎比牛奶和大豆过敏儿童更常见(分别为81%和74%)。两组儿童呼吸道症状的发生率相似。差异无统计学意义。
由于与IgE相关的牛奶过敏儿童中大豆蛋白过敏的患病率较高,水解配方奶粉似乎应该是儿童的首选。