Kunimatsu A, Abe O, Aoki S, Hayashi N, Okubo T, Masumoto T, Mori H, Yoshikawa T, Yamada H, Ohtomo K
Department of Radiology, Graduate School of Medicine, Tokyo University, 7-3-1 Hongo, Bunkyo-Ku 113-8655, Tokyo, Japan.
Neuroradiology. 2003 Aug;45(8):524-7. doi: 10.1007/s00234-002-0890-z. Epub 2003 Jul 19.
Little is known about the diffusion properties of brain lesions in neuro-Behçet's disease (NBD). We looked at 19 NBD lesions (13 active, six chronic) in six patients, using diffusion-weighted MRI (DWI). We calculated the apparent diffusion coefficients (ADC) of the lesions and compared them with normal contralateral brain, expressing this ratio as relative ADC (rADC). The rADC was 1.29+/-0.33 in active and 1.44+/-0.47 in chronic lesions, i.e., significantly higher than in the control regions. Increased diffusivity in both active and chronic phases in NBD is different from the pattern in ischaemic infarcts, so that ADC analysis might be helpful for differentiating between these conditions.
关于神经白塞病（NBD）中脑损伤的扩散特性，目前所知甚少。我们使用扩散加权磁共振成像（DWI）观察了6例患者的19个NBD损伤（13个活动期，6个慢性期）。我们计算了损伤的表观扩散系数（ADC），并将其与对侧正常脑区进行比较，将该比值表示为相对ADC（rADC）。活动期损伤的rADC为1.29±0.33，慢性期损伤的rADC为1.44±0.47，即显著高于对照区域。NBD活动期和慢性期扩散率的增加与缺血性梗死的模式不同，因此ADC分析可能有助于区分这些情况。
