Josan R, Lenghel A, Gidaly M, Pîrvu C, Grecu F, Dumitraşcu D, Szantay L
Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Bacteriol Virusol Parazitol Epidemiol. 1975 Oct-Dec;20(4):239-43.
The phenomenon of endointestinal protein exudation in acute infectious enterocolitis is studied. Total proteins were determined in 30 cases of acute enterocolitis and 50 of bacillary dysentery in the acute stages of the disease and convalescence. The proteinogram of the jejunal juice was performed in the acute stage and convalescence in 20 patients. In 16 patients and 5 controls endointestinal albumin elimination was determined quantitatively by means of 131I labeled albumin. The results showed increase in the total protein content in the jejunal juice in the course of acute infectious enterocolitis and bacillary dysentery and a return to normal values in convalescence. Electrophoresis of the jejunal juice in acute infectious enterocolitis showed the absence of fraction III with alpha1-globulin migration, and increased fractions I, II and IV probably due to the loss of endointestinal albumin, also confirmed by quantitative albumin determinations with 131I labeled albumin. In conclusion, patients with acute infectious enterocolitis present a marked loss of endointestinal albumins in the acute stage of the disease, with a return to normal values in convalescence.
对急性感染性小肠结肠炎中肠内蛋白质渗出现象进行了研究。在30例急性小肠结肠炎患者和50例急性细菌性痢疾患者的疾病急性期及恢复期测定了总蛋白。对20例患者在急性期和恢复期进行了空肠液蛋白图谱分析。对16例患者和5例对照者采用131I标记白蛋白定量测定肠内白蛋白清除情况。结果显示，在急性感染性小肠结肠炎和细菌性痢疾病程中，空肠液总蛋白含量增加，恢复期恢复至正常水平。急性感染性小肠结肠炎时空肠液电泳显示，缺乏具有α1球蛋白迁移的Ⅲ组分，Ⅰ、Ⅱ和Ⅳ组分增加，这可能是由于肠内白蛋白丢失所致，131I标记白蛋白定量测定白蛋白也证实了这一点。总之，急性感染性小肠结肠炎患者在疾病急性期肠内白蛋白明显丢失，恢复期恢复至正常水平。
