采用快速近红外分光光度法（NIRS）对缺血性前臂肌肉进行氧合测定。

Muscle oxygenation by fast near infrared spectrophotometry (NIRS) in ischemic forearm.

作者信息

De Blasi R A, Quaglia E, Gasparetto A, Ferrari M

机构信息

Department of Anesthesiology and Critical Care, I University of Rome La Sapienza, Policlinico Umberto I, Italy.

出版信息

Adv Exp Med Biol. 1992;316:163-72. doi: 10.1007/978-1-4615-3404-4_19.

DOI:10.1007/978-1-4615-3404-4_19

PMID:1288076

Abstract

Fast scanning near infrared spectroscopy (680-1050nm) was utilized to evaluate human forearm muscle oxygenation in 15 adults volunteers. Spectra were recorded in hypoxic hypoxia, ischemia and venous outflow restriction. Derivative spectra were performed with the aim to obtain a quantitative information of Hb/Mb oxygen saturation free from volume and scattering changes. The absorption spectra O.D. demonstrate an increase of deoxy-Hb/Mb in hypoxic condition with a moderate volume changes. In ischemia a rapid Hb/Mb desaturation occurred until a plateau was reached at 4th min. The cuff release was followed by hyperemia with Hb volume raise and oxy-Hb/Mb increase above the control. Spectral data support the hypothesis that derivative NIRS can be used to identify muscle oxygenation changes.

摘要

使用快速扫描近红外光谱法（680 - 1050nm）评估15名成年志愿者的前臂肌肉氧合情况。在低氧性低氧、缺血和静脉流出受限的情况下记录光谱。进行导数光谱分析的目的是获得不受体积和散射变化影响的血红蛋白/肌红蛋白氧饱和度的定量信息。吸收光谱光密度显示，在低氧条件下，脱氧血红蛋白/肌红蛋白增加，伴有适度的体积变化。在缺血过程中，血红蛋白/肌红蛋白迅速去饱和，直到第4分钟达到平台期。松开袖带后出现充血，血红蛋白体积增加，氧合血红蛋白/肌红蛋白高于对照水平。光谱数据支持这样的假设，即导数近红外光谱可用于识别肌肉氧合变化。