Bossert T, Rahmel A, Gummert J F, Battellini R, Mohr F W
Klinik für Herzchirurgie, Universität Leipzig, Herzzentrum.
Zentralbl Chir. 2003 Jul;128(7):573-5. doi: 10.1055/s-2003-40816.
A 71-year-old male patient presented with a 4-month history of fever, dyspnoea, night sweat, ankle swelling and was admitted to our institution for further investigation due to heart failure (NHYA IV). A posterior-anterior chest radiograph showed an enlarged cardiac silhouette, the lung was without pathological findings; calcifications were not described. Echocardiography revealed a severe diastolic malfunction but no pericardial effusion. In computed tomography, pericardium was thickened. Patient was admitted for further investigations. Heart catheterization revealed a left ventricular ejection fraction of 56 %, a cardiac index of 1.3 ml/min/m2 leading to the diagnosis of severe constrictive pericarditis. The patient underwent an urgent pericardectomy via median sternotomy. Extracorporal circulation was not necessary. The postoperative course was uneventful, heart failure improved to NYHA II. The removed pericardium revealed severe granulomatous pericarditis resulting from infection with acid-resistant bacilli. The diagnosis was confirmed by a positive culture for mycobacterium tuberculosis. The patient was put on anti-TB chemotherapy for one year. 1 year after operation patient is graduated in NYHA class II.
This rare extrapulmonary form of TB can have an insidious or sudden onset. The diagnosis is complicated by non-specific clinical and radiographic findings. Clinical presentation may be the result of the infectious process itself or the pericardial inflammation causing pain, effusion, and hemodynamic effects. In the absence of concurrent extracardiac TB, diagnosis of pericardial TB is difficult. Nevertheless, rapid diagnosis and treatment are crucial to reduce mortality.
一名71岁男性患者,有4个月发热、呼吸困难、盗汗、脚踝肿胀病史,因心力衰竭(纽约心脏协会IV级)入住我院进一步检查。后前位胸片显示心脏轮廓增大,肺部无病理表现;未描述钙化情况。超声心动图显示严重舒张功能障碍,但无心包积液。计算机断层扫描显示心包增厚。患者入院进一步检查。心脏导管检查显示左心室射血分数为56%,心脏指数为1.3 ml/min/m²,诊断为严重缩窄性心包炎。患者通过正中胸骨切开术接受了紧急心包切除术。无需体外循环。术后过程顺利,心力衰竭改善至纽约心脏协会II级。切除的心包显示由耐酸杆菌感染导致的严重肉芽肿性心包炎。结核分枝杆菌培养阳性证实了诊断。患者接受了一年的抗结核化疗。术后1年患者纽约心脏协会分级为II级。
这种罕见的肺外结核形式可能隐匿起病或突然起病。诊断因非特异性临床和影像学表现而复杂化。临床表现可能是感染过程本身或心包炎症导致疼痛、积液和血流动力学效应的结果。在无并发心外结核的情况下,心包结核的诊断困难。然而,快速诊断和治疗对于降低死亡率至关重要。