Takahashi Masataka, Kinouchi Hiroyuki, Sasajima Toshio, Suzuki Akira, Mizoi Kazuo
Department of Neurosurgery, Akita University School of Medicine, Akita 1-1-1 Hondo, Akita, 010-8543, Japan.
No Shinkei Geka. 2003 Jul;31(7):775-9.
A rare case in presented of a patient with edema formation along the optic pathway, which was caused by metastatic suprasellar tumor mimicking craniopharyngioma. A 63-year-old female with visual disturbance, diabetes insipidus, and symptomatic panhypopituitarism was admitted to our hospital. CT images showed a suprasellar mass lesion. MR images demonstrated a heterogeneously enhanced tumor and edema along the optic nerve and tract. Although no cystic component is shown in radiological findings, these features are commonly observed in cases of craniopharyngioma. The patient underwent removal of the tumor by the transcranial approach. Since histological examination revealed adenocarcinoma, the tumor was diagnosed as metastatic brain tumor originating from non-recurrent rectal cancer operated on eight years previously. Conventional radiotherapy with a dose of 50GY was performed for the residual tumor. The tumor size was unchanged, but the edema had disappeared 7 months after the operation. Edema spreading along the optic tract was reported as a characteristic MR finding for diagnosis of craniopharyngiomas as distinguished from other common parasellar tumors. However, it is suggested that edema of the optic pathway seems to be caused not only by craniopharyngioma but also other suprasellar lesions. Even if there was a characteristic radiological finding for some specific diseases, metastasis should be kept in mind as a differential diagnosis, because of its various appearance in neuroimages.
本文报告了一例罕见病例,患者视路出现水肿,由模仿颅咽管瘤的鞍上转移瘤引起。一名63岁女性因视力障碍、尿崩症和症状性全垂体功能减退入住我院。CT图像显示鞍上有占位性病变。MR图像显示肿瘤不均匀强化,视神经和视束有水肿。尽管影像学检查未显示囊性成分,但这些特征在颅咽管瘤病例中较为常见。患者接受了经颅肿瘤切除术。组织学检查显示为腺癌,因此该肿瘤被诊断为起源于八年前接受手术的非复发性直肠癌的脑转移瘤。对残留肿瘤进行了50GY的常规放疗。肿瘤大小未变,但术后7个月水肿消失。视束周围水肿被报道为诊断颅咽管瘤与其他常见鞍旁肿瘤的特征性MR表现。然而,提示视路水肿似乎不仅由颅咽管瘤引起,也可由其他鞍上病变引起。即使某些特定疾病有特征性影像学表现,由于转移瘤在神经影像中的表现多样,在鉴别诊断时也应考虑转移瘤。