慢性铍病的磨玻璃样计算机断层扫描表现：病理基础与演变

Ground-glass computed tomography pattern in chronic beryllium disease: pathologic substratum and evolution.

作者信息

Naccache Jean-Marc, Marchand-Adam Sylvain, Kambouchner Marianne, Guillon François, Monnet Isabelle, Girard Frederic, Brauner Michel, Valeyre Dominique

机构信息

Services de Pneumologie, Assistance Publique-Hôpitaux de Paris, Hôpital Avicenne, 125 rue de Stalingrad, 93009 Bobigny, France.

出版信息

J Comput Assist Tomogr. 2003 Jul-Aug;27(4):496-500. doi: 10.1097/00004728-200307000-00007.

DOI:10.1097/00004728-200307000-00007

PMID:12886131

Abstract

Five cases of chronic beryllium disease with predominant or isolated diffuse ground-glass lung opacities on computed tomography are reported with correlation to lung pathology. The ground-glass attenuation was either homogeneous and isolated (n = 1) or patchy and clearly predominant (n = 4) over linear and nodular opacities. In 4 cases, histologic samples showed a prominent diffuse involvement of the alveolar-capillary walls by florid granulomas. Evolution under corticosteroid was remarkable by the appearance of small-sized cysts in 3 cases.

摘要

报告了5例慢性铍病患者，其计算机断层扫描显示主要为或孤立的弥漫性磨玻璃样肺混浊，并与肺病理学相关。磨玻璃样衰减要么是均匀且孤立的（n = 1），要么是斑片状且明显占主导的（n = 4），超过线性和结节状混浊。在4例患者中，组织学样本显示肺泡毛细血管壁有明显的弥漫性炎性肉芽肿浸润。3例患者在使用皮质类固醇治疗后出现小囊肿，病情显著好转。