Voiculescu C, Bălăşoiu M, Turculeanu A, Filipaş L, Popescu E, Sava M, Tieranu E, Cupşa A
Faculty of Medicine, Department of Microbiology, Craiova, Romania.
Rev Roum Virol. 1992 Jan-Jun;43(1-2):59-66.
By testing 2362 children and infants from Craiova (Romania), for both HIV-antibody and HBs-antigen presence in the blood, a high rate of positivity was noticed in orphanages and in dystrophia units. A rate of "signal" (i.e. about 4% for HIV-antibodies, and 2.5% for HIV-antibody/HBs antigen), in hospitalized patients (pediatric service), was found as well. Four reasons support the horizontal way of virus transmission as the main route: most of seropositive subjects belong to 1-to-3-year age range, suggesting a virtual contamination before introduction of disposable syringes in Romania care units and hospitals; many HIV-seropositive cases have received frequent parenteral treatments, during repeated hospitalizations for acute respiratory disease; only few of the mothers of seropositive infants exhibited HIV-antibody presence; a relatively high rate of "double" seropositivity, i.e. HIV-antibody/HBs antigen, within tested serum samples was noticed.
通过对来自罗马尼亚克拉约瓦的2362名儿童和婴儿进行血液中HIV抗体和HBs抗原检测，发现孤儿院和营养不良病房的阳性率很高。在住院患者（儿科）中也发现了一定比例的“信号”（即HIV抗体约为4%，HIV抗体/HBs抗原约为2.5%）。有四个原因支持病毒以水平传播方式作为主要传播途径：大多数血清阳性者年龄在1至3岁之间，这表明在罗马尼亚医疗机构和医院引入一次性注射器之前就可能已受到感染；许多HIV血清阳性病例在因急性呼吸道疾病反复住院期间接受过频繁的肠胃外治疗；血清阳性婴儿的母亲中只有少数检测出HIV抗体呈阳性；在检测的血清样本中发现了相对较高比例的“双重”血清阳性，即HIV抗体/HBs抗原。
