Meffert R M
Department of Periodontics, Louisiana State University School of Dentistry, New Orleans 70119.
Implant Dent. 1992 Spring;1(1):25-33. doi: 10.1097/00008505-199200110-00003.
This article describes treatment of the ailing implant (bone loss with pocketing but static at the maintenance checks) and the failing implant (bone loss with pocketing, bleeding upon probing, purulence, and evidence of continuing bone loss irrespective of therapy). Because the surface of the implant is contaminated with endotoxin, it must be detoxified before any regenerative therapy. Studies have shown that citric acid is effective in detoxifying the hydroxyapatite-coated surfaces while tetracycline is more effective in sterilizing the metallic substrate fixtures. Guided tissue regeneration is useful as a "barrier" to prevent exfoliation of the grafted material. Both nonresorbable and resorbable materials have been used with great success. Allografts (freeze-dried bone) and alloplasts (synthetic materials) may be used to achieve a sulcus of decreased depth and possibly some type of osseous regeneration. The author recommends the use of the allograft if the surface is completely detoxified and the alloplast if it is not certain that the surface is sterilized and free of endotoxin. The allograft, being resorbable, will not effect biologic healing against a contaminated surface; hence, the use of the alloplast to "fill" the defect and prevent epithelial invagination.
本文描述了对患病种植体(出现骨丧失伴牙周袋形成,但在维护检查时处于静止状态)和失败种植体(骨丧失伴牙周袋形成、探诊出血、有脓性分泌物,且无论采用何种治疗方法均有持续骨丧失迹象)的治疗。由于种植体表面被内毒素污染,在进行任何再生治疗之前必须对其进行解毒处理。研究表明,柠檬酸对羟基磷灰石涂层表面的解毒有效,而四环素对金属基底固定装置的杀菌更有效。引导组织再生作为一种“屏障”,可防止移植材料脱落,已成功使用了不可吸收和可吸收材料。同种异体移植物(冻干骨)和异质移植物(合成材料)可用于使龈沟深度减小,并可能实现某种类型的骨再生。作者建议,如果种植体表面已完全解毒,则使用同种异体移植物;如果不确定表面是否已消毒且无内毒素,则使用异质移植物。同种异体移植物是可吸收的,在污染表面上不会影响生物愈合;因此,使用异质移植物来“填充”缺损并防止上皮内陷。