Akesson A, Fiori G, Krieg T, van den Hoogen F H, Seibold J R
Lund University Hospital, Lund, Sweden.
Clin Exp Rheumatol. 2003;21(3 Suppl 29):S5-8.
This report makes recommendations for standardized techniques of data gathering and collection regarding: 1) skin involvement 2) joint and tendon involvement, and 3) involvement of the skeletal muscles. The recommendations in this report derive from a critical review of the available literature and group discussion. Committee recommendations are considered appropriate for descriptive clinical investigation, translational studies and as standards for clinical practice. Skin involvement should be assessed using the modified Rodnan skin score. Joint involvement, when symmetric synovitis is present, could be best assessed by the DAS-28 as is utilized in rheumatoid arthritis. Clinical assessment should include a routinized evaluation for the presence and number of palpable tendon friction rubs. Muscle involvement should be screened for by performance of the serum creatine phosphokinase assay and assessment of proximal weakness. More specific testing including EMG, magnetic resonance imaging and muscle biopsy should be employed in those patients with clinically significant myopathy only.
1)皮肤受累情况;2)关节和肌腱受累情况;3)骨骼肌受累情况。本报告中的建议源自对现有文献的批判性综述以及小组讨论。委员会的建议被认为适用于描述性临床研究、转化研究以及作为临床实践标准。皮肤受累情况应使用改良的罗德南皮肤评分进行评估。当存在对称性滑膜炎时,关节受累情况最好通过类风湿关节炎中使用的DAS-28进行评估。临床评估应包括对可触及的肌腱摩擦音的存在和数量进行常规评估。应通过血清肌酸磷酸激酶测定和近端肌无力评估来筛查肌肉受累情况。仅对那些具有临床显著肌病的患者采用更具体的检测方法,包括肌电图、磁共振成像和肌肉活检。