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接受血管腔内修复的动脉瘤的主髂形态学相关性

Aortoiliac morphologic correlations in aneurysms undergoing endovascular repair.

作者信息

Ouriel Kenneth, Tanquilut Eugene, Greenberg Roy K, Walker Esteban

机构信息

Department of Vascular Surgery, The Cleveland Clinic Foundation, Desk S40, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

出版信息

J Vasc Surg. 2003 Aug;38(2):323-8. doi: 10.1016/s0741-5214(03)00318-5.

Abstract

PURPOSE

The feasibility of endovascular aneurysm repair depends on morphologic characteristics of the aortoiliac segment. Knowledge of such characteristics is relevant to safe deployment of a particular device in a single patient and to development of new devices for use in patients with a broader spectrum of anatomic variations.

METHODS

We evaluated findings on computed tomography scans for 277 patients being considered for endovascular aneurysm repair. Aortic neck length and angulation estimates were generated with three-dimensional trigonometry. Specific centerline points were recorded, corresponding to the aorta at the celiac axis, lowest renal artery, cranial aspect of the aneurysm sac, aortic terminus, right hypogastric artery origin, and left hypogastric origin. Aortic neck thrombus and calcium content were recorded, and neck conicity was calculated in degrees. Statistical analysis was performed with the Spearman rank correlation. Data are expressed as median and interquartile range.

RESULTS

Median diameter of the aneurysms was 52 mm (interquartile range, 48-59 mm) in minor axis and 56 mm (interquartile range, 51-64 mm) in major axis, and median length was 88 mm (interquartile range, 74-103 mm). Median proximal aortic neck diameter was 26 mm (interquartile range, 22-29 mm), and median neck length was 30 mm (interquartile range, 18-45 mm). The common iliac arteries were similar in diameter (right artery, 16 mm [interquartile range, 13-20 mm]; left artery, 15 mm [interquartile range, 11-18 mm]) and length (right, 59 mm [interquartile range, 50-69 mm]; left, 60 mm [interquartile range, 49-70 mm]). Median angulation of the infrarenal aortic neck was 40 degrees (interquartile range, 29-51 degrees), and median angulation of the suprarenal segment was 45 degrees (interquartile range, 36-57 degrees). By gender, sac diameter, proximal neck diameter, and iliac artery diameter were significantly larger in men. Significant linear associations were identified between sac diameter and sac length, neck angulation, and iliac artery diameter. As the length of the aneurysm sac increased the proximal aortic neck length decreased. Conversely, as the sac length decreased sac eccentricity increased. Mural thrombus content within the neck increased with increasing neck diameter.

CONCLUSIONS

There is considerable variability in aortoiliac morphologic parameters. Significant associations were found between various morphologic variables, links that are presumably related to a shared pathogenesis for aberration in aortoiliac diameter, length, and angulation. Ultimately this information can be used to develop new endovascular devices with broader applicability and improved long-term results.

摘要

目的

血管内动脉瘤修复的可行性取决于腹主动脉髂动脉段的形态特征。了解这些特征对于在单个患者中安全部署特定装置以及开发用于具有更广泛解剖变异患者的新装置至关重要。

方法

我们评估了277例考虑进行血管内动脉瘤修复患者的计算机断层扫描结果。使用三维三角测量法生成主动脉颈部长度和角度估计值。记录特定的中心线点,对应于腹腔干轴、最低肾动脉、动脉瘤囊的头侧、主动脉末端、右下腹动脉起源和左下腹动脉起源处的主动脉。记录主动脉颈部血栓和钙含量,并计算颈部锥度(以度为单位)。采用Spearman等级相关性进行统计分析。数据以中位数和四分位数间距表示。

结果

动脉瘤短轴中位数直径为52mm(四分位数间距为48 - 59mm),长轴中位数直径为56mm(四分位数间距为51 - 64mm),中位数长度为88mm(四分位数间距为74 - 103mm)。近端主动脉颈部中位数直径为26mm(四分位数间距为22 - 29mm),颈部中位数长度为30mm(四分位数间距为18 - 45mm)。双侧髂总动脉直径相似(右侧动脉,16mm[四分位数间距为13 - 20mm];左侧动脉,15mm[四分位数间距为11 - 18mm]),长度也相似(右侧,59mm[四分位数间距为50 - 69mm];左侧,60mm[四分位数间距为49 - 70mm])。肾下腹主动脉颈部中位数角度为40度(四分位数间距为29 - 51度),肾上段中位数角度为4度(四分位数间距为36 - 57度)。按性别分析,男性的动脉瘤囊直径、近端颈部直径和髂动脉直径明显更大。在动脉瘤囊直径与囊长度、颈部角度和髂动脉直径之间发现了显著的线性关联。随着动脉瘤囊长度增加,近端主动脉颈部长度减少。相反,随着囊长度减少,囊偏心度增加。颈部壁内血栓含量随颈部直径增加而增加。

结论

腹主动脉髂动脉形态学参数存在相当大的变异性。在各种形态学变量之间发现了显著关联,这些关联可能与腹主动脉髂动脉直径、长度和角度异常的共同发病机制有关。最终,这些信息可用于开发适用性更广、长期效果更好的新型血管内装置。

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