Soumah M T, Sylla A I, Toure M R, Camara T, Kama M L, Diallo M B, Cisse A
Clinique de chirurgie orthopédique et traumatologie, Centre Hospitalier Universitaire Ignace Deen, Conakry, République de Guinée.
Med Trop (Mars). 2003;63(1):49-52.
Analysis of 92 cases of quadriceps fibrosis following intramuscular injection into the thigh showed that the most affected age group was 3- to 7-year-old preschool children with a male predominance (68.7%). The most implicated drug (81.7% of cases) was quinine salts after of mean of 2 injections. Stiffness of the knee was the most outstanding clinical sign. In our series, the efficient technique for prompt functional recovery consisted of lengthening the quadriceps tendon by isolated "Z" plasty (56.5% of cases). Administration of drugs in oral, rectal or intravenous forms is the most effective means of prevention.
对92例大腿肌肉注射后发生股四头肌纤维化的病例分析表明,受影响最严重的年龄组是3至7岁的学龄前儿童,男性居多(占68.7%)。最常涉及的药物(81.7%的病例)是奎宁盐,平均注射2次后出现。膝关节僵硬是最突出的临床体征。在我们的系列病例中,促进功能迅速恢复的有效技术是通过单独的“Z”成形术延长股四头肌肌腱(56.5%的病例)。口服、直肠或静脉给药是最有效的预防手段。