Eskunov P N, Semchenko V V
Department of Histology, Cytology and Embryology, Omsk Medical Academy.
Morfologiia. 2003;123(2):60-4.
The aim of this study was to examine the myocardial histohematic barriers during the rehabilitation period after a cardiac arrest for 10 min. The electron histochemical analysis was applied to evaluate the permeability of histohematic barriers, to assess their ultrastructure and calcium localization. During 24 hours post resuscitation the destructive and compensatory-adaptive changes were found in the microcirculatory bed, accompanied by a pericapillary space edema, selective elevation of sarcolemmal permeability and calcium redistribution in cardiomyocytes. The structural and functional disturbances of histohematic barriers following the total ischemia are important factors of myocardial reperfusion lesions and of cardiodepression.
本研究的目的是检查心脏骤停10分钟后康复期的心肌组织血液屏障。应用电子组织化学分析来评估组织血液屏障的通透性，评估其超微结构和钙定位。在复苏后的24小时内，在微循环床中发现了破坏和代偿适应性变化，伴有毛细血管周围间隙水肿、肌膜通透性选择性升高和心肌细胞内钙重新分布。全脑缺血后组织血液屏障的结构和功能紊乱是心肌再灌注损伤和心功能抑制的重要因素。
