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过氧化油对家兔实验性动脉粥样硬化发展的影响。

Effects of peroxidized oil on the development of experimental atherosclerosis in rabbits.

作者信息

Gulati J, Gupta P P, Soni G L, Vadhera S, Singh R

机构信息

Department of Biochemistry and Veterinary Pathology, Punjab Agricultural University, Ludhiana.

出版信息

Indian Heart J. 1992 Jul-Aug;44(4):235-9.

PMID:1289221
Abstract

Ingestion of peroxidized oil under hypercholesterolemic dietary conditions resulted in a number of biochemical and pathological changes in rabbits. Total lipids, cholesterol and glyceride levels of plasma, liver and aorta were significantly higher in peroxidized oil fed rabbits, compared to the ones receiving normal oil. The degree of atherosclerosis and the severity of histopathological changes were significantly higher in rabbits fed with peroxidized oil.

摘要

在高胆固醇饮食条件下摄入过氧化油会导致兔子出现一系列生化和病理变化。与喂食正常油的兔子相比，喂食过氧化油的兔子血浆、肝脏和主动脉中的总脂质、胆固醇和甘油酯水平显著更高。喂食过氧化油的兔子动脉粥样硬化程度和组织病理学变化的严重程度显著更高。

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