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早期类风湿性关节炎患者第五跖趾关节的磁共振成像与传统X线摄影的比较

Magnetic resonance imaging of the fifth metatarsophalangeal joint compared with conventional radiography in patients with early rheumatoid arthritis.

作者信息

Forslind K, Johanson A, Larsson E M, Svensson B

机构信息

Rheumatology Section, Department of Medicine, Helsingborg's lasarett, Helsingborg, Sweden.

出版信息

Scand J Rheumatol. 2003;32(3):131-7. doi: 10.1080/03009740310002452.

DOI:10.1080/03009740310002452
PMID:12892248
Abstract

OBJECTIVE

To evaluate if magnetic resonance imaging (MRI) is superior to conventional radiography for detection of erosions in the fifth metatarsophalangeal (MTP5) joint.

METHODS

Within one year from the onset of rheumatoid arthritis (RA) (baseline), one and three years thereafter MRI and conventional radiographs of the MTP5 joint were performed in 23 patients.

RESULTS

MRI revealed erosions in 10 patients at baseline, in 15 after one year and in 15 patients after 3 years. On conventional radiography, there were erosions in 10 patients at baseline, 16 after one year as well as after 3 years. The agreement between the two imaging methods was fair to good at baseline and after one and three years (kappa 0,65, 0,51 and 0,51 respectively). The number of patients with clinical evidence of synovitis decreased considerably over time although the number of patients with MRI-synovitis was unchanged and the number of patients with erosions increased.

CONCLUSIONS

MRI was not superior to conventional radiography in detecting erosions in MTP5 joints in patients with early RA. Most erosions developed during the first year of observation. Synovitis on MRI may be a marker of future development of erosions in the MTP5 joint.

摘要

目的

评估磁共振成像(MRI)在检测第五跖趾关节(MTP5)侵蚀方面是否优于传统X线摄影。

方法

在类风湿关节炎(RA)发病后一年内(基线期),以及此后的一年和三年,对23例患者进行了MTP5关节的MRI和传统X线摄影检查。

结果

MRI显示,基线期有10例患者存在侵蚀,一年后有15例,三年后有15例。传统X线摄影显示,基线期有10例患者存在侵蚀,一年后和三年后均为16例。两种成像方法之间的一致性在基线期、一年后和三年后为中等至良好(kappa值分别为0.65、0.51和0.51)。尽管MRI显示滑膜炎的患者数量未变且侵蚀患者数量增加,但有滑膜炎临床证据的患者数量随时间显著减少。

结论

在早期RA患者中,MRI在检测MTP5关节侵蚀方面并不优于传统X线摄影。大多数侵蚀在观察的第一年出现。MRI上的滑膜炎可能是MTP5关节未来侵蚀发展的一个标志。

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Conventional radiography requires a MRI-estimated bone volume loss of 20% to 30% to allow certain detection of bone erosions in rheumatoid arthritis metacarpophalangeal joints.
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