Huang Shao-guang, Li Qing-yun
Shanghai Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China.
Zhonghua Jie He He Hu Xi Za Zhi. 2003 May;26(5):268-72.
To investigate the prevalence of obstructive sleep apnea-hypopnea syndrome (OSAHS) in adults aged over 30 yr in Shanghai, to provide data for estimating the burden of this disease and making strategies for treatment and prevention of this disorder.
9,600 subjects (aged >or= 30 yr) were derived from a random sample of the population living in six streets, four districts in Shanghai. They were asked to answer the questions from a questionnaire concerning snoring, daytime sleepiness, and habits such as smoking and drinking, etc. According to the degree of snoring, 150 moderate and severe snorers were selected to be tested by portable PSG for whole night data. The prevalence of OSAHS was conservatively estimated from the result.
8,081 subjects (84.18%) had answered the questions, among them 6,826 (84.47%) were available for evaluation. The prevalence of ever snoring was 57.11%, moderate and severe ones 23.73%. Before the age of 70, the prevalence of snoring increased with age, and higher in males than females, particularly for moderate and severe snoring. Smoking and drinking were associated with the severity of snoring. The prevalence was higher in women post-menopause and with irregular menstruation. ESS was significantly different among snorers with various severities. When AHI >or= 5 was taken as the cut-point, the prevalence of OSAHS was 20.39%. After excessive daytime sleepiness (EDS) definited as ESS >or= 9 was added as a criterian, the conservatively estimated prevalence of OSAHS was 3.62%.
The estimated prevalence of OSAHS in adults over 30 yr old was 3.62%. This can be a great burden to public health and implies that the disease needs better understanding and study.
调查上海30岁以上成年人阻塞性睡眠呼吸暂停低通气综合征（OSAHS）的患病率，为评估该病负担及制定防治策略提供依据。
从上海市四个区六条街道的居民中随机抽取9600名30岁及以上的受试者。让他们回答有关打鼾、日间嗜睡以及吸烟、饮酒等习惯的问卷问题。根据打鼾程度，选取150名中重度打鼾者进行便携式多导睡眠图（PSG）整夜检测。根据检测结果保守估计OSAHS的患病率。
8081名受试者（84.18%）回答了问题，其中6826名（84.47%）可用于评估。既往打鼾患病率为57.11%，中重度打鼾患病率为23.73%。70岁之前，打鼾患病率随年龄增长而升高，男性高于女性，尤其是中重度打鼾。吸烟和饮酒与打鼾严重程度相关。绝经后及月经不规律的女性患病率较高。不同严重程度打鼾者的Epworth嗜睡量表（ESS）得分有显著差异。以呼吸暂停低通气指数（AHI）≥5为切点，OSAHS患病率为20.39%。将日间过度嗜睡（EDS）定义为ESS≥9作为标准加入后，保守估计OSAHS患病率为3.62%。
30岁以上成年人中OSAHS的估计患病率为3.62%。这可能给公共卫生带来巨大负担，提示该病需要更好的认识和研究。
