Wei Silong, Zhang Yong, Guo Xiaojing, Yu Wenwen, Wang Meng, Yao Kan, Sun Hongxia, Zhang Hua, Lu Xiaofeng
Department of Oral and Craniomaxillofacial Sciences, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China.
Department of Stomatology, Shanghai Jiao Tong University affiliated Sixth People's Hospital, 600 Yishan Road, Shanghai, 200233, China.
Sleep Breath. 2017 Dec;21(4):853-860. doi: 10.1007/s11325-017-1484-7. Epub 2017 Mar 3.
Maxillomandibular advancement (MMA) is an effective alternative for treating severe obstructive sleep apnea (OSA). However, the promotion of MMA in China is limited by many Chinese patients having a convex facial profile. To achieve maximal upper airway enlargement without an esthetic disaster, we added counterclockwise rotation of the maxillomandibular complex (MMC) in the routine MMA. In this paper, we have evaluated the objective and subjective outcomes of this technology.
In total, 33 severe OSA patients who accepted counterclockwise maxillomandibular advancement (CMMA) were investigated in this study. Genioplasty, uvulopalatopharyngoplasty (UPPP), and turbinate reduction were also performed on selected patients. Polysomnography (PSG) and Epworth sleepiness scale (ESS) were chosen to evaluate the effectiveness of this technology in treating OSA. Patients' facial appearances were evaluated by cephalometric analysis and 5-point Likert scales.
After CMMA, the apnea-hypopnea index (AHI) decreased from 59.3 ± 14.6 to 10.2 ± 6.7 (P < 0.001), minimum SpO2 (pulse oxygen saturation, %) increased from 74.0 ± 11.7 to 88.8 ± 4.4 (P < 0.001), and ESS decreased from 12.5 ± 2.3 to 7.3 ± 2.1. It is encouraging that soft-tissue cephalometric measurements such as facial convexity angle, nasolabial angle, and labiomental fold were not worsening after surgery. The Likert scales revealed that 28 patients (85%) were satisfied or very satisfied with their facial changes. In addition, no patient complained about dental function after surgery.
These findings indicate that CMMA is an effective way to achieve a balance between airway enlargement and facial appearance for Chinese patients with severe OSA.
上颌下颌前徙术(MMA)是治疗重度阻塞性睡眠呼吸暂停(OSA)的一种有效替代方法。然而,由于许多中国患者面部轮廓凸出,MMA在中国的推广受到限制。为了在不造成美学灾难的情况下实现最大程度的上气道扩大,我们在常规MMA中增加了上颌下颌复合体(MMC)的逆时针旋转。在本文中,我们评估了该技术的客观和主观效果。
本研究共调查了33例接受逆时针上颌下颌前徙术(CMMA)的重度OSA患者。部分患者还进行了颏成形术、悬雍垂腭咽成形术(UPPP)和鼻甲切除术。选择多导睡眠图(PSG)和爱泼华嗜睡量表(ESS)来评估该技术治疗OSA的有效性。通过头影测量分析和5级李克特量表评估患者的面部外观。
CMMA术后,呼吸暂停低通气指数(AHI)从59.3±14.6降至10.2±6.7(P<0.001),最低血氧饱和度(脉搏血氧饱和度,%)从74.0±11.7升至88.8±4.4(P<0.001),ESS从12.5±2.3降至7.3±2.1。令人鼓舞的是,术后面部凸度角、鼻唇角和唇颏沟等软组织头影测量指标并未恶化。李克特量表显示,28例患者(85%)对其面部变化感到满意或非常满意。此外,术后没有患者抱怨牙齿功能。
这些结果表明,CMMA是一种有效的方法,可为中国重度OSA患者在气道扩大和面部外观之间实现平衡。