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急性胆囊炎患者的经皮胆囊造瘘术:美国一家转诊中心45例患者的经验

Percutaneous cholecystostomy in patients with acute cholecystitis: experience of 45 patients at a US referral center.

作者信息

Byrne Michael F, Suhocki Paul, Mitchell Robert M, Pappas Theodore N, Stiffler Helen L, Jowell Paul S, Branch Malcolm S, Baillie John

机构信息

Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.

出版信息

J Am Coll Surg. 2003 Aug;197(2):206-11. doi: 10.1016/S1072-7515(03)00143-1.

Abstract

BACKGROUND

Standard treatment for acute cholecystitis is cholecystectomy, but some patients are at high risk for immediate surgery. Percutaneous cholecystostomy might be the procedure of choice in this group. We reviewed the experience of percutaneous cholecystostomy in a large tertiary center population.

STUDY DESIGN

We performed a retrospective analysis of patients who underwent percutaneous cholecystostomy, and recorded indications for cholecystostomy, duration of tube placement, clinical outcome, death within 30 days of procedure, complications, bacteriology of aspirated bile, gallbladder contents, and performance of interval cholecystectomy.

RESULTS

Forty-five patients (mean age 63 years) had cholecystostomy tubes placed from July 1999 to March 2002. All had confirmed or presumed acute cholecystitis. Mean duration of tube insertion was 54.3 days. Thirty-six patients improved clinically within 5 days. Nine patients died within 30 days; only one death was directly related to gallbladder sepsis. Nine patients subsequently had laparoscopic cholecystectomy, eight had open cholecystectomy, and two had cholecystoenterostomy. Cholecystectomy was planned in another five patients. Cholecystostomy tubes leaked in two patients, blocked in four, and dislodged in one. One patient developed a hemoperitoneum. Bile aspirated at cholecystostomy was culture positive in 12 patients, negative in 16, and not sent or recorded in 17. Twenty-two patients had gallstones, 10 had sludge, 9 had both, and 4 had neither.

CONCLUSIONS

In experienced hands, percutaneous cholecystostomy is easy to perform, with low complication and high success rates. It is the procedure of choice in patients with acute cholecystitis unfit for emergency surgery. Patients often improve clinically, so that cholecystectomy can be done electively.

摘要

背景

急性胆囊炎的标准治疗方法是胆囊切除术,但有些患者立即进行手术的风险很高。经皮胆囊造瘘术可能是这类患者的首选治疗方法。我们回顾了在一个大型三级医疗中心对患者实施经皮胆囊造瘘术的经验。

研究设计

我们对接受经皮胆囊造瘘术的患者进行了回顾性分析,并记录了胆囊造瘘术的指征、置管时间、临床结局、术后30天内的死亡情况、并发症、吸出胆汁的细菌学检查结果、胆囊内容物以及二期胆囊切除术的实施情况。

结果

1999年7月至2002年3月期间,45例患者(平均年龄63岁)接受了胆囊造瘘管置入术。所有患者均确诊或疑似患有急性胆囊炎。平均置管时间为54.3天。36例患者在5天内临床症状改善。9例患者在30天内死亡;只有1例死亡与胆囊脓毒症直接相关。9例患者随后接受了腹腔镜胆囊切除术,8例接受了开腹胆囊切除术,2例接受了胆囊肠吻合术。另有5例患者计划进行胆囊切除术。2例患者的胆囊造瘘管发生渗漏,4例堵塞,1例移位。1例患者发生了腹腔积血。胆囊造瘘术吸出的胆汁培养结果为12例阳性,16例阴性,17例未送检或未记录。22例患者有胆结石,10例有胆泥,9例两者皆有,4例两者皆无。

结论

在经验丰富的医生手中,经皮胆囊造瘘术操作简便,并发症少,成功率高。它是不适于急诊手术的急性胆囊炎患者的首选治疗方法。患者的临床症状通常会改善,因此可以择期进行胆囊切除术。

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