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泌尿生殖系统横纹肌肉瘤的回顾性研究

A retrospective study on genito urinary Rhabdomyosarcoma.

作者信息

Rahman M M, Siddiqui T H, Amin M R, Islam K D, Hossain M S

机构信息

Department of Paediatric Surgery, BSMMU, Dhaka, Bangladesh.

出版信息

Mymensingh Med J. 2003 Jul;12(2):82-4.

Abstract

A retrospective study was carried out on Genitourinary Rhabdomyosarcoma in the Department of Paediatric Surgery of Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh during the period January 1990 to December 1999. Total thirteen patients were treated during this period, age ranging from 1 month to 12 years. Eight patients were male and five were female (M: F = 1.6: 1). Diagnosis was made by history, thorough physical examination, digital rectal examination, ultrasonography, intravenous urography, CT scan and biopsy. All the patients were treated with chemoradiation theraphy as a first line of management and surgical excision was done for local residual tumours. Eight children (61.5%) were asymptomatic after completion of chemo-radiation therapy. Three (23.07%) patients discontinued the chemo-radiation schedule. Residual mass was present in one (7.7%) case for which partial cystectomy was done and the patient died in the 5th post operative day. Another patient (7.7%) who had pulmonary metastasis at the time of diagnosis, died during chemo-radiation therapy.

摘要

1990年1月至1999年12月期间,在孟加拉国达卡的班加班杜·谢赫·穆吉布医科大学儿外科开展了一项关于泌尿生殖系统横纹肌肉瘤的回顾性研究。在此期间共治疗了13例患者,年龄从1个月至12岁不等。8例为男性,5例为女性(男∶女 = 1.6∶1)。通过病史、全面体格检查、直肠指检、超声检查、静脉肾盂造影、CT扫描及活检做出诊断。所有患者均首先接受放化疗,对局部残留肿瘤进行手术切除。8名儿童(61.5%)在完成放化疗后无症状。3例(23.07%)患者中断了放化疗疗程。1例(7.7%)患者有残留肿块,为此进行了部分膀胱切除术,该患者在术后第5天死亡。另1例患者(7.7%)在诊断时已有肺转移,在放化疗期间死亡。

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