Talukder S I, Huq M H, Rahman S, Haque M A, Sarker C B, Ali M S
Assistant Professor (CC), Department of Pathology, Mymensingh Medical College, Mymensingh, Bangladesh.
Mymensingh Med J. 2003 Jul;12(2):89-92.
To find out the epidemiological characteristics of the patients with Kala-azar attending to a pathology laboratory at Mymensingh we studied retrospectively in a total of 65 patients. These patients were suspected to be Kala-azar as they were suffering from usually chronic fever, anaemia and splenomegaly. They were referred for serological detection of anti-k39 Leishmanial antibody by Immunochromatographic test (ICT) method. ICT positive cases were included for study. Majority cases were suffering from fever of more than 3 months (40%). Out of 65 patients 43 (66.15%) were males and 22 (33.85%) were females with a M:F ratio 2:1. Patients of 10 or less then 10 years of age were 17 (26.15%), in 11-20 years 23 (35.38%), in 21-30 years 13 (20.00%), in 31-40 years 5 (7.69%), in 41-50 years (6.15%) and in more than 50 years 3 (4.62%). Distribution of patients in different districts were: Mymensingh 54 (83.08%), Tangail 5 (7.69%), Jamalpur (4.62%), Netrokona 1 (1.54%) and Kishorgonj 1 (1.54%). In Mymensingh district patients were distributed as following Upazilla:Trishal 22 (40.74%), Fulbaria 11 (20.37%), Mymensingh Sadar 7 (12.96%), Gaforgaon 7 (12.96%),Bhaluka 5 (9.96%), Fulpur 1 (1.85%) and Nandail 1 (1.85%). Patients were found to scattered among different Unions of the affected Upazillas. The details addresses of the Kala-azar patients are recorded in authors computer databases. This may help in the further study regarding pathogenesis, reservoir and vectors of Leishmania in endemic areas. It may also helps in the community based study of Kala-azar. Present study supports that Kala-azar is still prevailing in the south-western region of greater Mymensingh in Bangladesh of which males and the adolescents are more affected.
为了查明在迈门辛一家病理实验室就诊的黑热病患者的流行病学特征，我们对65例患者进行了回顾性研究。这些患者因经常患有慢性发热、贫血和脾肿大而疑似患有黑热病。他们被转诊通过免疫层析试验（ICT）方法进行抗k39利什曼原虫抗体的血清学检测。ICT阳性病例被纳入研究。大多数病例发热超过3个月（40%）。65例患者中，43例（66.15%）为男性，22例（33.85%）为女性，男女比例为2:1。10岁及以下的患者有17例（26.15%），11 - 20岁的有23例（35.38%），21 - 30岁的有13例（20.00%），31 - 40岁的有5例（7.69%），41 - 50岁的有4例（6.15%），50岁以上的有3例（4.62%）。不同地区患者的分布情况为：迈门辛54例（83.08%），唐盖尔5例（7.69%），贾马尔布尔4例（4.62%），内特拉科纳1例（1.54%），基肖尔贡杰1例（1.54%）。在迈门辛地区，患者按如下乡进行分布：特里沙尔22例（40.74%），富尔巴里11例（20.37%），迈门辛市7例（12.96%），加福尔贡7例（12.96%），巴卢卡5例（9.96%），富尔布尔1例（1.85%），南代尔1例（1.85%）。患者分布在受影响乡的不同联合村。黑热病患者的详细地址记录在作者的计算机数据库中。这可能有助于进一步研究利什曼原虫在流行地区发病机制、宿主和传播媒介，也有助于基于社区的黑热病研究。本研究支持黑热病在孟加拉国大迈门辛的西南部地区仍然流行，其中男性和青少年受影响更大。
