Zanolli Michael
Dermatology Consultants PC and Division of Dermatology, Vanderbilt University Medical Center, Nashville, TN 37205, USA.
J Am Acad Dermatol. 2003 Aug;49(2 Suppl):S78-86. doi: 10.1016/s0190-9622(03)01139-3.
The use of the various forms of phototherapy remains an essential treatment option for psoriasis vulgaris. Expertise concerning the mechanisms involved with the actions of therapeutic ultraviolet light and the proper delivery of office-based treatments resides within the specialty of dermatology. New therapies for the treatment of moderate to severe psoriasis will soon become available which have specific actions on the cutaneous immune system. A better understanding of the known mechanisms of action for ultraviolet light therapy makes it appropriate to include this area of treatment with new biologic agents. Photochemotherapy and various forms for delivery of narrow band ultraviolet B can be used as treatments, either as monotherapy or in combination with other agents, to effectively treat moderate and severe psoriasis.
各种形式的光疗仍然是寻常型银屑病的重要治疗选择。有关治疗性紫外线作用机制以及门诊治疗的正确实施方面的专业知识属于皮肤科范畴。治疗中度至重度银屑病的新疗法即将问世,这些疗法对皮肤免疫系统有特定作用。更好地理解紫外线光疗已知的作用机制使得将这一治疗领域与新型生物制剂相结合成为可能。光化学疗法以及各种窄谱中波紫外线照射方式可作为单一疗法或与其他药物联合使用,有效治疗中度和重度银屑病。