Bisley James W, Goldberg Michael E
David Mahoney Center of Brain and Behavior, Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, New York, New York, USA.
Adv Neurol. 2003;93:141-57.
The lateral intraparietal area has a signal that describes a saccade target, maintains the memory of a saccade plan during a delay, and describes the saccade itself. It is unlikely, however, that this signal generates a plan for the saccade, because most neurons with this delayed saccade activity also respond, sometimes more strongly, to salient stimuli that are unlikely to be saccade targets. Instead, it is more likely that this saccadic signal performs two functions unrelated to saccade planning itself. The first function is to contribute to a salience map: it is well known that attention is located at the goal of a saccadic eye movement, and recent experiments detailed here show that the attentional advantage of the saccade goal is [figure: see text] maintained throughout the delay period of a memory-guided saccade. The saccade signal, presumably driven by the frontal eye fields or other prefrontal cortical areas, informs the salience map of a saccade plan, and therefore renders the goal of the saccade a salient location for attentional processes and, possibly, to provide targets for future saccades. The second function is to use the saccade signal to provide information by which the parietal cortex can update the visual representation to compensate for an eye movement, thus maintaining a spatially accurate vector map of the visual world despite a moving eye.
顶内沟外侧区有一个信号,该信号描述扫视目标,在延迟期间保持扫视计划的记忆,并描述扫视本身。然而,这个信号不太可能产生扫视计划,因为大多数具有这种延迟扫视活动的神经元也会对不太可能成为扫视目标的显著刺激做出反应,有时反应更强。相反,这个扫视信号更有可能执行与扫视计划本身无关的两个功能。第一个功能是对显著性地图做出贡献:众所周知,注意力位于眼球扫视运动的目标处,这里详细介绍的最新实验表明,在记忆引导扫视的延迟期间,扫视目标的注意力优势得以保持。扫视信号大概由额叶眼区或其他前额叶皮质区域驱动,它将扫视计划告知显著性地图,从而使扫视目标成为注意力过程的显著位置,并可能为未来的扫视提供目标。第二个功能是利用扫视信号提供信息,顶叶皮质可以借此更新视觉表征以补偿眼球运动,从而在眼球移动的情况下仍能保持视觉世界在空间上准确的矢量地图。