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[突发性聋的预后因素]

[Prognostic factors in sudden deafness].

作者信息

Pajor Anna, Durko Tomasz, Gryczyński Maciej

机构信息

Klinika Laryngologii Katedry Otolaryngologii UM w Łodzi.

出版信息

Otolaryngol Pol. 2003;57(2):271-5.

PMID:12894435
Abstract

Sudden sensorineural hearing loss is still a diagnostic and therapeutic dilemma and is very difficult to predict recovery in it. Different factors may influence a prognosis like severity of hearing loss, duration of symptoms before treatment, presence of vertigo, type of audiogram and age of patients. The aim of the study was an evaluation of the hearing improvement in sudden deafness in relation to some of these elements. A retrospective analysis of 119 patients treated for sudden sensorineural hearing loss during 10 years was done. Clinical otolaryngological, neurological and ophthalmological examination, audiologic and ENG tests were carried out. Hearing improvement was obtained in 51 patients (43%). Hearing recovery was recorded in 38 patients (66%) in whom duration of disease before treatment was no longer than 7 days, in 9 patients (25%) with a period 8-14 days and in 4 patients (16%)--with period 15-30 days (66% vs 25% vs 16%, p < 0.001, 25% vs 16% p = 0.39). Hearing improvement was more frequent in patients with initially mild (51.6%) than severe (38.7%) and profound hearing loss (25%) (51.5% vs 25%, p < 0.05). Hearing recovery was observed in 18 patients (33.3%) with vertigo and in 33 patients (50.8%) without vertigo (p = 0.056). In analysis of age (five groups: until 30 years, 31-40 years, 41-50 years, 51-60 years, over 60 years) in comparison with hearing recovery it was not found any significance (45.5% vs 45.8% vs 46.4% vs 37% vs 38.9%, p = 0.94). It was stated that in patients with sudden deafness duration of the disease before treatment and level of hearing loss may significantly influence an outcome, also vertigo may worsen a recovery, contrary age of the patients does not seem as important prognostic factor.

摘要

突发性感音神经性听力损失仍然是一个诊断和治疗难题,且很难预测其恢复情况。不同因素可能会影响预后,如听力损失的严重程度、治疗前症状持续时间、是否存在眩晕、听力图类型以及患者年龄。本研究的目的是评估突发性耳聋患者的听力改善情况与其中一些因素的关系。对119例在10年间接受突发性感音神经性听力损失治疗的患者进行了回顾性分析。进行了临床耳鼻喉科、神经科和眼科检查、听力学及眼震电图检查。51例患者(43%)听力得到改善。在治疗前疾病持续时间不超过7天的38例患者(66%)、8 - 14天的9例患者(25%)以及15 - 30天的4例患者(16%)中记录到听力恢复(66%对25%对16%,p < 0.001;25%对16%,p = 0.39)。初始听力轻度损失的患者(51.6%)听力改善比重度(38.7%)和极重度听力损失患者(25%)更频繁(51.5%对25%,p < 0.05)。18例有眩晕的患者(33.3%)和33例无眩晕的患者(50.8%)观察到听力恢复(p = 0.056)。在分析年龄(分为五组:30岁及以下、31 - 40岁、41 - 50岁、51 - 60岁、60岁以上)与听力恢复的关系时,未发现显著差异(45.5%对45.8%对46.4%对37%对38.9%,p = 0.94)。研究表明,对于突发性耳聋患者,治疗前疾病持续时间和听力损失程度可能会显著影响预后,眩晕也可能会使恢复情况变差,相反,患者年龄似乎不是重要的预后因素。

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