Wei Xudong, He Jian
Department of Otolaryngology-Head and Neck Surgery, People's Hospital of Gansu Province, Lanzhou, 730000, China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2011 Jul;25(13):599-601.
To analysis the prognostic factors of the sudden sensorineural hearing loss (SHL), to predict the prognosis of patient with SHL precisely.
Two hundred and fifty-six cases (280 ears) with SHL were reviewed retrospectively during January 2005 to Jun 2009. Possible influence factor was analysis with logistic stepwise regression to investigate the correlation with prognosis. All verified influence factors was analysis with single-factor analysis of variance.
The prognosis of SHL related to age, the trouble time before treatment, vertigo with(or) tinnitus, degree of hearing loss, the patterns of audiogram, but not to sex and trouble ear. With increasing of age, the prognosis of SHL becomes poor. Especially after 40 years old, the prognosis gets worse. Regarding to the relationship between the trouble time before treatment and the prognosis. The groups within 9 days have no significant difference (P > 0.05). There are significant difference between group of > 3-9 days and > 9-15 days (P < 0.05), > 9-15 days and > 15 days (P < 0.05). Compared with patients suffer from vertigo or (and) tinnitus, patients without vertigo or (and) tinnitus obtain a good result (P < 0.05). As for initial hearing threshold, flat (upgrade) subgroup, downgrade (upgrade) subgroup, upgrade subgroup and valley-mountain subgroup have no significant difference (P > 0.05). However, there are significant difference between upgrade subgroup and flat subgroup, upgrade subgroup and all the others. Furthermore, comparison with the low,midst, severe and profound hearing loss, the prognosis among them is no statistical different. But statistical different exists between media and profound subgroup.
The factor of age, the trouble time before treatment, vertigo with (or) tinnitus, degree of hearing loss, the patterns of audiogram are correlated with prognosis of SHL. The prognosis has a poor tendency with age increasing, especially after 40 years old. Good result maybe achieved within 9 visiting days. After that, the recovery rates declined obviously. Patients have company complication, such as vertigo or (and) tinnitus have poor prognosis. The downgrade subgroup of audiogram has high incidence rate although upgrade subgroup has a good prognosis. The level of hearing loss before medication is not a simple linear correlation with prognosis. Media hearing loss demonstrate the best prognosis. On the contrary, profound hearing loss has the worst prognosis. With hearing threshold added, the total recovery rates goes down.
分析突发性聋（SHL）的预后因素，以准确预测SHL患者的预后。
回顾性分析2005年1月至2009年6月期间收治的256例（280耳）SHL患者。采用逻辑逐步回归分析可能的影响因素，以探讨其与预后的相关性。对所有验证的影响因素进行单因素方差分析。
SHL的预后与年龄、治疗前病程、眩晕伴（或）耳鸣、听力损失程度、听力图类型有关，而与性别和患耳无关。随着年龄的增加，SHL的预后变差。尤其是40岁以后，预后更差。关于治疗前病程与预后的关系。9天内的组间差异无统计学意义（P>0.05）。3 - 9天组与9 - 15天组、9 - 15天组与>15天组之间差异有统计学意义（P<0.05）。与伴有眩晕或（和）耳鸣的患者相比，无眩晕或（和）耳鸣的患者预后较好（P<0.05）。对于初始听力阈值，平坦（上升）亚组、下降（上升）亚组、上升亚组和谷峰亚组之间差异无统计学意义（P>0.05）。然而，上升亚组与平坦亚组、上升亚组与其他所有亚组之间存在显著差异。此外，与轻度、中度、重度和极重度听力损失相比，它们之间的预后无统计学差异。但中度与极重度亚组之间存在统计学差异。
年龄、治疗前病程、眩晕伴（或）耳鸣、听力损失程度、听力图类型等因素与SHL的预后相关。随着年龄增加预后有变差趋势，尤其是40岁以后。就诊9天内可能取得较好效果。此后，恢复率明显下降。伴有眩晕或（和）耳鸣等并发症的患者预后较差。听力图下降亚组发病率高，上升亚组预后较好。用药前听力损失程度与预后并非简单的线性关系。中度听力损失预后最佳。相反，极重度听力损失预后最差。随着听力阈值增加，总恢复率下降。
