[植物雌激素与癌症预防]
[Phytoestrogen and cancer prevention].
作者信息
Watanabe Shaw, Uesugi Sayo, Zhuo XingGang, Kimira Mitsuru
机构信息
Department of Applied Bioscience, Tokyo University of Agriculture, 1-1-1 Sakuraoka, Setagaya-ku, Tokyo 156-8502, Japan.
出版信息
Gan To Kagaku Ryoho. 2003 Jul;30(7):902-8.
Phytoestrogens are defined to be plant chemicals that modify estrogenic effects in the body by binding to the estrogen receptors in mammals. Isoflavones, coumestane, lignan, and prenylflavones are examples of these, with isoflavones from soy foods and lignans from rye being a major dietary contribution. Mechanisms of cancer prevention by these phytoestrogens are reviewed, and human epidemiological studies, especially for breast and prostate cancers, are summarized and the results discussed.
植物雌激素被定义为通过与哺乳动物体内的雌激素受体结合来改变体内雌激素效应的植物化学物质。异黄酮、香豆雌酚、木脂素和异戊烯基黄酮就是其中的例子，大豆食品中的异黄酮和黑麦中的木脂素是主要的膳食来源。本文综述了这些植物雌激素预防癌症的机制，并总结了人类流行病学研究，特别是关于乳腺癌和前列腺癌的研究，并对结果进行了讨论。
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