Tokunaga Toshiteru, Sumimura Junichi, Yoshidome Katsuhide, Fujita Shigeo, Tsuji Kou, Oota Fuminori, Tsuboyama Naohisa, Nagai Isamu
Dept. of Surgery, Kinan General Hospital.
Gan To Kagaku Ryoho. 2003 Jul;30(7):1009-11.
We encountered a patient with liver metastases from colorectal cancer in whom continuous hepatic arterial infusion brought complete remission. A 58-year-old man was admitted to our hospital for advanced rectal cancer with multiple liver metastases. He underwent a low anterior resection (D2). Continuous hepatic arterial infusion of 5-FU (250 mg/day) with a weekly arterial infusion of MMC (4 mg) was performed for 14 days. Six continuous hepatic arterial infusions resulted in a complete remission. The patient has been free from any sign of recurrence for 37 months after the operation. Continuous hepatic arterial infusion using 5-FU and MMC seems to be effective in the treatment of multiple liver metastases from colorectal cancer.
我们遇到一名患有结直肠癌肝转移的患者，通过持续肝动脉灌注实现了完全缓解。一名58岁男性因晚期直肠癌伴多发肝转移入住我院。他接受了低位前切除术（D2）。持续肝动脉灌注5-氟尿嘧啶（250毫克/天），每周动脉灌注丝裂霉素（4毫克），持续14天。六次持续肝动脉灌注导致完全缓解。术后37个月，患者无任何复发迹象。使用5-氟尿嘧啶和丝裂霉素进行持续肝动脉灌注似乎对治疗结直肠癌多发肝转移有效。
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