[肝动脉内化疗联合肝切除治疗转移性结直肠癌的经验]
[Experience in intra-hepatic-arterial chemotherapy and hepatic resection for metastatic colorectal cancer].
作者信息
Shimada H, Ozaki M, Ariga T, Ooshima I, Maruyama T, Kinoshita H, Takeda A, Yoshimura S, Shouko T
机构信息
Dept. of Surgery, Yokohama Rousai Hospital.
出版信息
Gan To Kagaku Ryoho. 1995 Sep;22(11):1570-2.
Out of 213 consecutive cases of colorectal cancer patients, 39 patients had liver metastasis (31 synchronous metastases and 8 metachronous metastases). One-and 3-year survivals of these patients with liver metastases were 46.5% and 30.1%, respectively. Twenty-four patients who were treated with intra-hepatic-arterial chemotherapy had better survival rates of 54.7% at 1 year, and 36.5% at 3 years than non-treated patients. Fifteen patients who underwent curative hepatic resection had better survival rates of 83.1% at 1 year, and 48.5% at 3 years than non-resected patients. Thirteen patients who underwent curative hepatic resection followed by intra-hepatic-arterial chemotherapy had good survival rates of 80.8% at 1 year, and 53.9% at 3 years. Seven patients who had multiple metastases to both lobes, were treated with intra-hepatic-arterial chemotherapy. These patients had a better survival rate of 22.9% at 1 year than non-treated patients.
在213例连续的结直肠癌患者中，39例发生了肝转移（31例同时性转移和8例异时性转移）。这些肝转移患者的1年和3年生存率分别为46.5%和30.1%。接受肝动脉内化疗的24例患者，其1年生存率为54.7%，3年生存率为36.5%，高于未接受治疗的患者。15例行根治性肝切除的患者，其1年生存率为83.1%，3年生存率为48.5%，高于未行肝切除的患者。13例行根治性肝切除后接受肝动脉内化疗的患者，1年生存率为80.8%，3年生存率为53.9%。7例两叶均有多发转移的患者接受了肝动脉内化疗。这些患者1年生存率为22.9%，高于未接受治疗的患者。
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