Li Sheng-li, Ouyang Shu-yuan, Chen Cong-ying, Liu Ju-ling, Guan Yong, Liao Yu-mei, Liu Hui-wen
Department of Ultrasound, Shenzhen Maternal and Childrens Health Hospital, Shenzhen 518028, China.
Zhonghua Fu Chan Ke Za Zhi. 2003 May;38(5):267-9.
To review the value of ultrasonographic evaluation on fetal limbs anatomy and malformations in prenatal diagnosis using a systematic continuous sequence approach (SCSA).
Successive 4,932 prenatal ultrasonographic evaluation during gestation aging 14 - 40 weeks from August 2000 to September 2002 entered the present review. SCSA was applied to scan each limb of the fetus respectively.
The anatomic structures of the four limbs of the fetus were clearly displayed and correctly recognized on ultrasonic images using the SCSA in 4 750 cases (96.3%). Ninety eight limb malformations of 34 fetuses were correctly diagnosed (87.2%). Whereas 16 malformations of 5 fetuses were missed to recognize (12.8%). The diagnoses were confirmed after subsequent labor or induced labor. The sensitivity, specificity, accuracy, positive and negative predictive values were 87.2%, 99.8%, 99.2%, 81.0% and 99.9%, respectively.
The majority of fetal limb structures and malformations can be clearly demonstrated on prenatal ultrasonic imaging using SCSA. SCSA for prenatal ultrasonographic evaluation of the fetal limbs is a reliable and accurate diagnostic modality so far as the skills become more sophisticated.
采用系统连续序列法（SCSA）回顾超声评估胎儿肢体解剖结构及畸形在产前诊断中的价值。
回顾2000年8月至2002年9月期间对4932例孕龄14 - 40周胎儿进行的连续产前超声评估。应用SCSA分别扫描胎儿的每个肢体。
4750例（96.3%）胎儿的四肢解剖结构在超声图像上通过SCSA清晰显示并被正确识别。34例胎儿的98处肢体畸形被正确诊断（87.2%）。而5例胎儿的16处畸形未被识别（12.8%）。诊断在随后的分娩或引产术后得到证实。敏感性、特异性、准确性、阳性预测值和阴性预测值分别为87.2%、99.8%、99.2%、81.0%和99.9%。
使用SCSA，大多数胎儿肢体结构及畸形在产前超声成像中可清晰显示。就目前技术越来越成熟的情况而言，SCSA用于产前超声评估胎儿肢体是一种可靠且准确的诊断方法。
