Stoll C, Alembik Y, Dott B, Roth M P
Institut de Puériculture, Hôpitaux Universitaires de Strasbourg, France.
Prenat Diagn. 1994 Sep;14(9):781-6. doi: 10.1002/pd.1970140903.
Prenatal diagnosis performed by ultrasound scan is now a routine part of antenatal care in our region. How many fetal anomalies are actually detected by this procedure? We have used our registry of congenital malformations to answer this question regarding limb reduction defects (LRDs). The mean time of detection of LRDs was 26 weeks of pregnancy (range 16-32 weeks). The sensitivity of prenatal diagnosis of LRDs by ultrasonographic examination was much lower for isolated malformations (fetuses with only one anomaly) than for multiply malformed children with LRDs, 4.0 and 18.2 per cent, respectively. For all cases of LRDs, the percentage of prenatal detection was 11.5. Termination of pregnancy was performed in 6.7 per cent of the cases.
超声扫描进行的产前诊断如今是我们地区产前护理的常规组成部分。通过该程序实际检测出了多少胎儿异常情况呢？我们利用先天性畸形登记册来回答有关肢体短小缺陷（LRDs）的这个问题。LRDs的平均检测时间为妊娠26周（范围为16 - 32周）。超声检查对孤立性畸形（仅有一种异常的胎儿）进行LRDs产前诊断的敏感性远低于患有LRDs的多发畸形儿童，分别为4.0%和18.2%。对于所有LRDs病例，产前检测的百分比为11.5%。6.7%的病例进行了妊娠终止。
