Fel'dman Iu M, Liubchich L S, Chudner V Z, Usachev G I, Shtefanek L A
Zh Mikrobiol Epidemiol Immunobiol. 1975 Oct(10):59-60.
It is recommended to use the capacity of pathogenic staphylococci to be lysed by polyvalent therapeutic staphylococcal bacteriophage in the capacity of an additional simple and accessible criterion of staphylococcus pathogenicity. Of 147 strains of the pathogenic plasmacoagulating staphylococci 101 were lysed by the phage and of 166 nonplasmocoagulating nonpathogenic strains--only 6. This test correlated with the other signs of staphylococcus (lecithinase and hemolytic activity). The simplicity and sufficient specificity of this test permits to use it in any practical laboratory. Polyvalent diagnostic phage can be used on the basis of therapeutic bacteriophage by its additional adaptation to the pathogenic strains of staphylococcus.
建议利用多价治疗性葡萄球菌噬菌体裂解致病性葡萄球菌的能力,作为葡萄球菌致病性的一项额外简单且易于获取的标准。在147株致病性血浆凝固葡萄球菌中,有101株可被该噬菌体裂解,而在166株非血浆凝固非致病性菌株中,只有6株可被裂解。该试验与葡萄球菌的其他特征(卵磷脂酶和溶血活性)相关。该试验的简单性和足够的特异性使其可在任何实际实验室中使用。多价诊断噬菌体可在治疗性噬菌体的基础上,通过使其进一步适应葡萄球菌致病菌株来使用。