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[关于血管弹性膜的组织化学研究,特别关注糖尿病。I. 蛋白质(作者译)]

[Histotopochemical investigations on elastic membranes of blood vessels with special regard to diabetes mellitus. I. Proteins (author's transl)].

作者信息

Opitz M, Hahn von Dorsche H

出版信息

Acta Histochem. 1975;54(1):16-23.

PMID:128978
Abstract

Histochemical investigations on elastic membranes of vessels under normally and diabetic conditions have been accomplished. These studies were made on man (diabetic and non-diabetic subjects) and on rats with streptozotocin-diabetes. The results are comparable among one another. The amino acids histidine, tyrosine and tryptophan were not demonstrable. The detection of primary NH2-groups (ninhydrin-Schiff-method and o-diacetylbenzen-reaction) was positive however. The results of the reactions in healthy men and animals were more distinct than in diabetic human subjects and animals. In healthy children the intensities of the histochemically reactions were higher than in adults.

摘要

已完成对正常和糖尿病状态下血管弹性膜的组织化学研究。这些研究针对人类(糖尿病患者和非糖尿病患者)以及链脲佐菌素诱导糖尿病的大鼠进行。结果相互可比。未检测到氨基酸组氨酸、酪氨酸和色氨酸。然而,对伯氨基(茚三酮 - 席夫法和邻二乙酰苯反应)的检测呈阳性。健康人和动物的反应结果比糖尿病患者和动物更明显。在健康儿童中,组织化学反应的强度高于成年人。

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