Synthesis and interaction studies of watersoluble nucleic acid analogs containing serine as a spacer.
作者信息
Wada T, Masumi N, Mochizuki E, Inaki Y, Takemoto K
机构信息
Faculty of Engineering, Osaka University, Japan.
出版信息
Nucleic Acids Symp Ser. 1992(27):115-6.
PMID:1289784
Abstract
Watersoluble nucleic acid analogs containing L- or D-serine as a spacer were synthesized. Thymine was used as nucleic acid bases of these analogs. The base contents of these analogs were 93-94%. These analogs were found to form stable polymer complexes with Poly A or DNA by specific base-base interaction, which were observed from hypochromicity of UV spectra. In both cases, the maximum hypochromicity values of PEI-L-Ser-Thy were higher than that of PEI-D-Ser-Thy.
摘要
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