Lis-Sochocka Marta, Zarebska Alicja, Cichacz-Kwiatkowska Beata, Łańcut MirosŁaw, Koziej Jacek, Czerny Krystyna
Department and Institute of Histology and Embryology, Medical University of Lublin.
Ann Univ Mariae Curie Sklodowska Med. 2002;57(1):181-6.
The Loeventhal gland of the white Wistar rats was examined. The animals were given Metizol for 21 days and 42 days at the dose of 1 mg/kg b.m./24 h. The Loeventhal gland's samples were taken for histological and histochemical examination. Then they there stained with hematoxylin and eosin, Masson's, PAS's, and Feulgen's method. The mean area of section of cell nuclei was measured. Results of examination were counted statistically. The following changes were noticed: after 21 days of administration of Metizol in the Loeventhal gland the mean area of the section of cells nuclei was decreased; after 42 days of administration of Metizol the mean area of the section of cell nuclei was decreased as well, but to a lesser degree than in group 1. New follicles appeared which can be the expression of cell mitotic activity.
对白色Wistar大鼠的洛温塔尔腺进行了检查。给动物以1毫克/千克体重/24小时的剂量服用美替唑21天和42天。采集洛温塔尔腺样本进行组织学和组织化学检查。然后用苏木精和伊红、马森氏、PAS氏和福尔根氏方法进行染色。测量细胞核切片的平均面积。对检查结果进行统计学计数。观察到以下变化：服用美替唑21天后，洛温塔尔腺细胞核切片的平均面积减小；服用美替唑42天后，细胞核切片的平均面积也减小，但程度小于第1组。出现了新的滤泡，这可能是细胞有丝分裂活性的表现。
