Friis-Møller Alice, Lüneborg-Nielsen Margrethe
Department of Clinical Microbiology, H:S Hvidovre Hospital, Copenhagen, Denmark.
Ann Univ Mariae Curie Sklodowska Med. 2002;57(1):540-3.
Bacteriuria (> or = 10(5) CFU/ml) is a very common phenomenon in elderly people, occurring twice as frequently in women than in men. There are symptomatic and asymptomatic types of bacteriuria. Risk factors include: a decrease in the estrogen level in women after the menopause, catheterisation, urinary bladder dysfunction, hypertrophy of the prostate gland, diabetes, neurological illnesses. The diagnosis of bacteriuria is based on quantitative urine culture (positive result--> or = 10(5) CFU/ml bacteriae). The most frequent pathogens are: E. coli, enterococci, staphylococci, Pseudomonas aeruginosa, Proteus mirabilis. The antimicrobial therapy is not advised for asymptomatic bacteriuria. In the case of symptomatic bacteriuria it is advised to take urine for culture and to perform sensitivity testing as well as blood culture and to start a "blind therapy". In order to use the antimicrobial treatment effectively, the most frequently occurring pathogens should be registered and their sensitivity patterns in the given hospital recognised.
菌尿症(≥10⁵CFU/ml)在老年人中是一种非常常见的现象,在女性中的发生率是男性的两倍。菌尿症有症状性和无症状性两种类型。危险因素包括:女性绝经后雌激素水平下降、导尿、膀胱功能障碍、前列腺肥大、糖尿病、神经系统疾病。菌尿症的诊断基于定量尿培养(阳性结果→≥10⁵CFU/ml细菌)。最常见的病原体是:大肠杆菌、肠球菌、葡萄球菌、铜绿假单胞菌、奇异变形杆菌。对于无症状菌尿症,不建议进行抗菌治疗。对于有症状的菌尿症,建议采集尿液进行培养并进行药敏试验,同时进行血培养并开始“经验性治疗”。为了有效使用抗菌治疗,应记录最常见的病原体及其在特定医院的药敏模式。