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网织红细胞的成熟。II. 源自应激网织红细胞的红细胞寿命。

The maturation of reticulocytes. II. Life-span of red cells originating from stress reticulocytes.

作者信息

Shimada A

出版信息

Acta Med Okayama. 1975 Aug;29(4):283-9.

PMID:128992
Abstract

Life-spans of macroreticuloytes and macrocytic red cells were studied. Rabbits were made anemic by injecting phenylhydrazine. Peripheral blood rich in reticulocytes was drawn, labeled with 3H-amino acids, and injected back into the anemic animal. Autoradiographic observation on circulating red cells revealed that macroreticulocytes matured at nearly the same time as normal-sized reticulocytes but that the macrocytic red cells had a short life-span compared to normal-sized red cells.

摘要

对大网织红细胞和大红细胞的寿命进行了研究。通过注射苯肼使兔子贫血。抽取富含网织红细胞的外周血,用³H -氨基酸进行标记,然后回注到贫血动物体内。对循环红细胞的放射自显影观察显示,大网织红细胞与正常大小的网织红细胞几乎同时成熟,但与正常大小的红细胞相比,大红细胞的寿命较短。

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引用本文的文献

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Modeling time variant distributions of cellular lifespans: increases in circulating reticulocyte lifespans following double phlebotomies in sheep.细胞寿命的时变分布建模:绵羊重复放血后循环网织红细胞寿命的增加
J Pharmacokinet Pharmacodyn. 2008 Jun;35(3):285-323. doi: 10.1007/s10928-008-9089-1. Epub 2008 Jun 14.
2
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J Pharmacokinet Pharmacodyn. 2007 Aug;34(4):519-47. doi: 10.1007/s10928-007-9056-2. Epub 2007 May 22.
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Pharmacodynamic analysis of changes in reticulocyte subtype distribution in phlebotomy-induced stress erythropoiesis.
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J Pharmacokinet Pharmacodyn. 2005 Aug;32(3-4):359-76. doi: 10.1007/s10928-005-0009-3.