Shi R, Liu X, Fang W, Zhou B, Li S, Li F
Department of Nuclear Medicine, Cardiovascular Institute and Fu Wai Hospital, CAMS & PUMC, Beijing 100037.
Chin Med Sci J. 2000 Mar;15(1):64-6.
The aim of this study was to detect coronary artery disease using 99mTc-MIBI myocardial perfusion imaging in patients with valvular disease.
Thirty patients with valvular disease confirmed by echocardiography underwent 99mTc-MIBI myocardial perfusion imaging using multiSPECT 1h after stress test (exercise, dipyridamole or dobutamine test) and were performed coronary angiography within 1 month before valvular operation.
For 29 out of the 30 patients, the results of 99mTc-MIBI myocardial perfusion imaging were similar with those of coronary angiography, the concordance rate was 96.7% and the negative predictability was 100%.
99Tc-MIBI myocardial perfusion imaging is a reliable non-invasive method for detecting coronary artery disease in patients with valvular disease and so as to draw up suitable operation programs for them.
本研究旨在利用99mTc-MIBI心肌灌注显像检测瓣膜病患者的冠状动脉疾病。
30例经超声心动图确诊为瓣膜病的患者在负荷试验（运动、双嘧达莫或多巴酚丁胺试验）后1小时使用多探头SPECT进行99mTc-MIBI心肌灌注显像，并在瓣膜手术前1个月内进行冠状动脉造影。
30例患者中有29例99mTc-MIBI心肌灌注显像结果与冠状动脉造影结果相似，符合率为96.7%，阴性预测值为100%。
99Tc-MIBI心肌灌注显像是检测瓣膜病患者冠状动脉疾病的可靠无创方法，可为其制定合适的手术方案。
