Hamodrakas S J
Department of Biochemistry, Cell and Molecular Biology, and Genetics, University of Athens, Panepistimiopolis, Greece.
Results Probl Cell Differ. 1992;19:115-86. doi: 10.1007/978-3-540-47207-0_6.
I will not attempt to summarize this chapter, which is already a summary. I merely wish to point out that experimental and theoretical evidence to date clearly suggests that antiparallel beta-pleated sheet dictates self-assembly in helicoidal proteinaceous eggshells. Molecular details of this process have started to become clear after the development of the specific, most probably correct, protein structural models in the case of the silkmoths, where amino acid information is available and with the help of several experimental techniques. However, for people seeking universal mechanisms the picture should still be far from complete. Several analogous systems should be studied before providing final answers.
我不会试图总结这已经是一篇总结的章节。我只想指出，迄今为止的实验和理论证据清楚地表明，反平行β折叠片层决定了螺旋状蛋白质蛋壳中的自组装。在蚕蛾的案例中，在有氨基酸信息且借助多种实验技术建立了特定的、很可能正确的蛋白质结构模型之后，这个过程的分子细节开始变得清晰。然而，对于寻求通用机制的人来说，情况仍远未完整。在给出最终答案之前，应该研究几个类似的系统。
