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子痫孕产妇死亡率

Maternal mortality rates in eclampsia.

作者信息

López-Llera M, Rubio Linares G, Hernández Horta J L

出版信息

Am J Obstet Gynecol. 1976 Jan 15;124(2):149-55. doi: 10.1016/s0002-9378(16)33291-4.

Abstract

This study evaluates the dominant factors that influence the course of eclampsia toward a lethal outcome by means of statistical analysis of various clinical, laboratory, and morphologic data of 365 cases of toxemia with convulsions, that included 49 deaths and 33 autopsies, registered during a 9 year period. This communication suggests that the death of eclamptic patients resulted from a combination of several factors that showed a very wide individual variation. Since advancing age of the mother was associated with a high incidence of coincidental renal and vascular diseases, this was the most clearly influential factor. The presence of twins, delay in hospitalization, under haste in deciding upon cesarean delivery, and underestimation of the initial clinical condition were all influential factors, although without statistical significance. Cesarean section, performed in 141 instances of ante- and intrapartum eclasmpsia (40.4 per cent), was not associated with a higher maternal mortality rate.

摘要

本研究通过对365例惊厥性毒血症病例的各种临床、实验室和形态学数据进行统计分析,评估了影响子痫病程发展至致命结局的主要因素。这些病例是在9年期间登记的,其中包括49例死亡病例和33例尸检病例。本报告表明,子痫患者的死亡是由多种因素共同作用导致的,这些因素在个体间存在很大差异。由于母亲年龄的增长与并发肾脏和血管疾病的高发生率相关,因此这是最明显的影响因素。双胞胎的存在、住院延迟、决定剖宫产时的仓促以及对初始临床状况的低估都是影响因素,尽管没有统计学意义。在141例子痫前期和产时子痫病例(占40.4%)中进行了剖宫产,这与较高的孕产妇死亡率无关。

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