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[分析化学在新药研发中的作用]

[Role of analytical chemistry in the development of new drugs].

作者信息

Zhou T H

机构信息

Institute of Materia Medica, CAMS, PUMC, Beijing 100050, China.

出版信息

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2001 Dec;23(6):537-9.

Abstract

In this paper, the role of analytical chemistry in drug research, its development and some basic research related to developing new drugs are concisely discussed, including the establishment of quality control standards, finger prints of natural medicine products, resolution of chiral compounds and drug metabolism studies. The incorrect point of view of some people on pharmaceutical analysis is mentioned and the indispensability of this discipline in drug research and development is also emphasized.

摘要

本文简要讨论了分析化学在药物研究中的作用、其发展以及与新药研发相关的一些基础研究,包括质量控制标准的建立、天然药物产品的指纹图谱、手性化合物的拆分以及药物代谢研究。文中提到了一些人对药物分析的错误观点,并强调了该学科在药物研发中的不可或缺性。

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