Wang Daming, Ling Feng, Wang Anshun, Cai Yiling, Li Meng
Department of Neurosurgery, Beijing Hospital, Beijing 100730.
Chin Med Sci J. 2003 Mar;18(1):59-62.
To compare the embolization effects of intracranial aneurysm with mechanical detachable spirals (MDS) and with Guglielmi detachable coils (GDC).
One hundred and twenty cases with 125 intracranial aneurysms were embolized in Beijing Hospital from March 1995 to July 1999. Sixty-six aneurysms in 64 cases were embolised with MDS, 51 in 48 with GDC, and 8 in 8 with both MDS and GDC. Clinical data including sex, age, subarachnoid hemorrhage (SAH), Hunt & Hess grading, diameter and neck width of aneurysms, number and length of coils used per aneurysm, occlusive ratio, and complications were compared between MDS and GDC groups.
MDS and GDC group were comparable (t-test or chi2-test, all P value > 0.10) in terms of age, sex, diameter of aneurysms [(8.46 +/- 3.42) mm vs. (7.38 +/- 3.45) mm], neck width [(3.49 +/- 1.50) mm vs. (3.26 +/- 1.52) mm], coils number [(4.65 +/- 3.01) vs. (4.24 +/- 2.65)] and their length [(460.2 +/- 398.5) mm vs. (422.9 +/- 387.1) mm] used per aneurysm, occlusive ratio in aneurysms embolized > or = 80% [(95.00% +/- 6.32%) vs. (94.19% +/- 7.63%)], mortality and permanent complications (7.8% vs. 4.2%).
MDS and GDC are all materials for embolization of intracranial aneurysms. MDS is less expensive, but more difficult to control and of propensity to complications while GDC is more compliant, easier to be used, safer, and have many alternative types for use as well a more extensive indications.
比较机械可脱性弹簧圈（MDS）与 Guglielmi 可脱性弹簧圈（GDC）栓塞颅内动脉瘤的效果。
1995 年 3 月至 1999 年 7 月在北京医院对 120 例患者的 125 个颅内动脉瘤进行栓塞治疗。64 例患者的 66 个动脉瘤采用 MDS 栓塞，48 例患者的 51 个动脉瘤采用 GDC 栓塞，8 例患者的 8 个动脉瘤同时采用 MDS 和 GDC 栓塞。比较 MDS 组和 GDC 组的临床资料，包括性别、年龄、蛛网膜下腔出血（SAH）、Hunt & Hess 分级、动脉瘤直径和瘤颈宽度、每个动脉瘤使用的弹簧圈数量和长度、闭塞率及并发症。
MDS 组和 GDC 组在年龄、性别、动脉瘤直径[（8.46±3.42）mm 对（7.38±3.45）mm]、瘤颈宽度[（3.49±1.50）mm 对（3.26±1.52）mm]、每个动脉瘤使用的弹簧圈数量[（4.65±3.01）对（4.24±2.65）]及其长度[（460.2±398.5）mm 对（422.9±387.1）mm]、栓塞后动脉瘤闭塞率≥80%者的闭塞率[（95.00%±6.32%）对（94.19%±7.63%）]、死亡率及永久性并发症（7.8%对 4.2%）方面具有可比性（t 检验或卡方检验，所有 P 值＞0.10）。
MDS 和 GDC 均为颅内动脉瘤栓塞材料。MDS 价格较低，但控制难度较大且并发症发生率较高；而 GDC 顺应性更好，使用更简便、更安全，有多种可供选择的类型且适应证更广泛。
