颅内动脉瘤采用机械可脱性螺旋圈与 Guglielmi 可脱性弹簧圈栓塞术的初步比较。

Initial comparison of intracranial aneurysm embolization with mechanical detachable spirals and with Guglielmi detachable coils.

作者信息

Wang Daming, Ling Feng, Wang Anshun, Cai Yiling, Li Meng

机构信息

Department of Neurosurgery, Beijing Hospital, Beijing 100730.

出版信息

Chin Med Sci J. 2003 Mar;18(1):59-62.

PMID:12901531

Abstract

OBJECTIVE

To compare the embolization effects of intracranial aneurysm with mechanical detachable spirals (MDS) and with Guglielmi detachable coils (GDC).

METHODS

One hundred and twenty cases with 125 intracranial aneurysms were embolized in Beijing Hospital from March 1995 to July 1999. Sixty-six aneurysms in 64 cases were embolised with MDS, 51 in 48 with GDC, and 8 in 8 with both MDS and GDC. Clinical data including sex, age, subarachnoid hemorrhage (SAH), Hunt & Hess grading, diameter and neck width of aneurysms, number and length of coils used per aneurysm, occlusive ratio, and complications were compared between MDS and GDC groups.

RESULTS

MDS and GDC group were comparable (t-test or chi2-test, all P value > 0.10) in terms of age, sex, diameter of aneurysms [(8.46 +/- 3.42) mm vs. (7.38 +/- 3.45) mm], neck width [(3.49 +/- 1.50) mm vs. (3.26 +/- 1.52) mm], coils number [(4.65 +/- 3.01) vs. (4.24 +/- 2.65)] and their length [(460.2 +/- 398.5) mm vs. (422.9 +/- 387.1) mm] used per aneurysm, occlusive ratio in aneurysms embolized > or = 80% [(95.00% +/- 6.32%) vs. (94.19% +/- 7.63%)], mortality and permanent complications (7.8% vs. 4.2%).

CONCLUSIONS

MDS and GDC are all materials for embolization of intracranial aneurysms. MDS is less expensive, but more difficult to control and of propensity to complications while GDC is more compliant, easier to be used, safer, and have many alternative types for use as well a more extensive indications.

摘要

目的

比较机械可脱性弹簧圈（MDS）与 Guglielmi 可脱性弹簧圈（GDC）栓塞颅内动脉瘤的效果。

方法

1995 年 3 月至 1999 年 7 月在北京医院对 120 例患者的 125 个颅内动脉瘤进行栓塞治疗。64 例患者的 66 个动脉瘤采用 MDS 栓塞，48 例患者的 51 个动脉瘤采用 GDC 栓塞，8 例患者的 8 个动脉瘤同时采用 MDS 和 GDC 栓塞。比较 MDS 组和 GDC 组的临床资料，包括性别、年龄、蛛网膜下腔出血（SAH）、Hunt & Hess 分级、动脉瘤直径和瘤颈宽度、每个动脉瘤使用的弹簧圈数量和长度、闭塞率及并发症。

结果

MDS 组和 GDC 组在年龄、性别、动脉瘤直径[（8.46±3.42）mm 对（7.38±3.45）mm]、瘤颈宽度[（3.49±1.50）mm 对（3.26±1.52）mm]、每个动脉瘤使用的弹簧圈数量[（4.65±3.01）对（4.24±2.65）]及其长度[（460.2±398.5）mm 对（422.9±387.1）mm]、栓塞后动脉瘤闭塞率≥80%者的闭塞率[（95.00%±6.32%）对（94.19%±7.63%）]、死亡率及永久性并发症（7.8%对 4.2%）方面具有可比性（t 检验或卡方检验，所有 P 值＞0.10）。