Spira Alexander I, Carducci Michael A
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 1650 Orleans Street, CRB Room 1M89, Baltimore, MD 21231, USA.
Curr Opin Pharmacol. 2003 Aug;3(4):338-43. doi: 10.1016/s1471-4892(03)00081-x.
Differentiation therapy is an area of oncology that is in its infancy. Theoretically, the concept of differentiation therapy involves turning a cancer cell "off" biologically and reverting to a more "benign" phenotype. Many agents have been studied over the past few years, with many already either in use clinically or showing future promise.