含鸟嘌呤和胞嘧啶的六核苷酸与水溶性碳二亚胺的缩合反应。

Condensation reaction of hexanucleotides containing guanine and cytosine with water soluble carbodiimide.

作者信息

Kawamura K, Okamoto F

机构信息

Department of Applied Chemistry, College of Engineering, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan.

出版信息

Nucleic Acids Symp Ser. 2000(44):217-8. doi: 10.1093/nass/44.1.217.

DOI:10.1093/nass/44.1.217

PMID:12903346

Abstract

The condensation reactions of hexanucleotides involving guanine and cytosine in the presence of water-soluble carbodiimide (WSC) have been investigated as a model reaction of the prebiotic formation of RNA under primitive earth. The reactions formed cyclic hexanucleotides and dimers in which the product yields were dependent on the sequence.

摘要

作为原始地球上RNA益生元形成的模型反应，已对在水溶性碳二亚胺（WSC）存在下涉及鸟嘌呤和胞嘧啶的六核苷酸缩合反应进行了研究。这些反应形成了环状六核苷酸和二聚体，其中产物产率取决于序列。