Guo J, Ke M, Qin M, Wang Z
Department of Gastroenterology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2000 Oct;22(5):416-20.
To explore the physiological function of the midgastric-transverse band (MTB) in the modification of intragastric food distribution in digestive period.
18 healthy subjects(HS) and 18 patients with functional dyspepsia(FD) participated in this study. After fasting over 8 hours all subjects took 150 ml of milk (777 J) mixed with 150 g Magnesium Sulfate, and laid supinely on 30 degrees angle with horizontal line, X-ray films were taken at 0, 30, 60, and 90 minutes after the meal, respectively. Analyzed parameters included the width of MTB, the total, proximal and distal gastric area (TGA, PGA and DGA), the ratio of proximal and distal stomach during every 30 minutes period, the correlation between MTB and PGA, MTB and DGA.
(1) There was significant difference of MTB and DGA in every period postprandially (P < 0.05 or 0.01), by contrast, there were no significant differences of TGA or PGA between HS and FD except at TGA 90 min (P < 0.05). (2) There were close correlation between MTB and PGA at 0 (P < 0.01), 30 (P < 0.01), 60 min (P < 0.01) after the meal in HS, but only at 0 min (P < 0.01) in FD. Also close correlations between MTB and DGA at 60 (P < 0.01) and 90 min (P < 0.01) in HS, but in FD. (3) the ratios of PGA from 0-30 min and 60-90 min in FD significantly decreased respectively, however the other ratios were shown no significant difference between HS and FD during each period. (4) there were close correlations between PGA and MTB at 0, 30, 60 min after the meal in HS, however except 0 min there were no correlations in FD. By contrast, between DGA and MTB there were close correlations at 60, or 90 min in HS, no correlation in FD at any time point.
MTB may play an important role in modifying intragastric food distribution in HS, while the dysfunction of MTB may result in the distal gastric overloading in FD, the mechanism of MTB needs further studies.
探讨胃中部横带（MTB）在消化期改变胃内食物分布的生理功能。
18名健康受试者（HS）和18名功能性消化不良（FD）患者参与本研究。所有受试者禁食8小时以上后，饮用150 ml牛奶（777焦耳）与150 g硫酸镁的混合液，然后以与水平线呈30度角仰卧，分别在进食后0、30、60和90分钟拍摄X线片。分析参数包括MTB宽度、胃总面积、近端和远端胃面积（TGA、PGA和DGA）、每30分钟期间近端和远端胃的比例、MTB与PGA、MTB与DGA之间的相关性。
（1）餐后各时段MTB和DGA有显著差异（P<0.05或0.01），相比之下，HS和FD之间TGA或PGA除90分钟时TGA有显著差异（P<0.05）外无显著差异。（2）HS餐后0（P<0.01）、30（P<0.01）、60分钟（P<0.01）时MTB与PGA密切相关，而FD仅在0分钟时（P<0.01）相关。HS在60（P<0.01）和90分钟（P<0.01）时MTB与DGA也密切相关，但FD中无。（3）FD中0 - 30分钟和60 - 90分钟的PGA比例分别显著下降，然而各时段HS和FD之间的其他比例无显著差异。（4）HS餐后0、30、60分钟时PGA与MTB密切相关，而FD除0分钟外无相关性。相比之下，HS在60或90分钟时DGA与MTB密切相关，FD在任何时间点均无相关性。
MTB可能在HS中改变胃内食物分布方面起重要作用，而MTB功能障碍可能导致FD患者远端胃负荷过重，MTB的机制需要进一步研究。
