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[细胞减灭术(腹膜切除术)及腹腔内热灌注化疗:一种治疗腹膜假黏液瘤的创新且有效的方法]

[Cytoreductive surgery (peritonectomy) and intraperitoneal hyperthermic chemotherapy: an innovative and effective approach to the treatment of pseudomyxoma peritonei].

作者信息

Deraco M, Kusamura S, Gronchi A

机构信息

Istituto Nazionale Tumori, Milano.

出版信息

Tumori. 2003 Jul-Aug;89(4 Suppl):54-5.

Abstract

Pseudomyxoma peritonei is a rare disease characterized by a complete redistribution of mucin into the peritoneal cavity. Thirty three PMP patients referred to National Cancer Institute of Milan were submitted to 34 consecutive procedures of peritonectomy and intra peritoneal hyperthermic perfusion (IPHP). Five yrs overall survival has been 96% while 3 yrs PFS 68%. Morbility, mortality and toxicity were 18, 3 and 9% respectively. Peritonectomy associated with IPHP is the most indicated approach to cure patients with DPAM and IFG, subgroup of pseudomyxoma peritonei.

摘要

腹膜假黏液瘤是一种罕见疾病,其特征为黏液素在腹腔内完全重新分布。33例转诊至米兰国家癌症研究所的腹膜假黏液瘤患者接受了34次连续的腹膜切除术和腹腔内热灌注(IPHP)。5年总生存率为96%,而3年无进展生存率为68%。发病率、死亡率和毒性分别为18%、3%和9%。腹膜切除术联合IPHP是治疗腹膜假黏液瘤亚型弥漫性腹膜腺瘤样黏液瘤(DPAM)和肠型黏液性肿瘤(IFG)患者的最适宜方法。

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