Egger H, Kindermann G, Eberlein F
Arch Gynakol. 1975 Dec 16;220(1):43-54. doi: 10.1007/BF00673147.
During laparoscopy we performed 132 ovarian punch biopsies in seventy one amenorrhoeic patients. With increasing experience, laparoscopic ovarian biopsy is a valuable element in the examination of amenorrhoeic patients. Biopsy specimens with an edge length of 4-5 mm for surface and depth can be obtained during laparoscopy under general anaesthesia without any great risk or difficulty. When performed bilaterally, it provides a representative picture of the cellular structure and function of the ovaries and thus makes a contribution to the prognosis of a disturbance in the endocrine regulating-circuit of ovarian function. In addition, the ovarian biopsy provides information about the basic gonadotrophic situation of the patient as a longitudinal section. It should be included in the synopsis of all endocrine and genetic parameters of a patient, particularly in clinic in which the morphological substrate of disturbed functions and apparent diseases is still examined.
在腹腔镜检查过程中，我们对71例闭经患者进行了132次卵巢穿刺活检。随着经验的增加，腹腔镜卵巢活检是闭经患者检查中的一个重要环节。在全身麻醉下进行腹腔镜检查时，可以获取边缘长度为4 - 5毫米的表面和深度活检标本，且没有太大风险或困难。双侧进行时，它能提供卵巢细胞结构和功能的代表性图像，从而有助于判断卵巢功能内分泌调节回路紊乱的预后。此外，卵巢活检作为纵向切片，能提供患者基本促性腺激素情况的信息。它应纳入患者所有内分泌和遗传参数的概要中，特别是在仍对功能障碍和明显疾病的形态学基础进行检查的临床环境中。
