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骨癌风险评估

Bone cancer risk estimates.

作者信息

Puskin J S, Nelson N S, Nelson C B

机构信息

U.S. Environmental Protection Agency, Washington, D.C. 20460.

出版信息

Health Phys. 1992 Nov;63(5):579-80. doi: 10.1097/00004032-199211000-00011.

DOI:10.1097/00004032-199211000-00011
PMID:1290512
Abstract

Due to confusion between endosteal (bone surface) dose and average skeletal dose, ICRP 60 has substantially overestimated the risk of radiogenic bone cancer. This confusion apparently stems from an incorrect reading of the BEIR IV report, which does not clearly draw this distinction. It should also be noted that what appear to be summary numerical risk estimates for bone sarcoma induction in BEIR IV and BEIR V refer only to average skeletal dose as calculated for 224Ra.

摘要

由于骨内膜(骨表面)剂量与平均骨骼剂量之间的混淆,国际放射防护委员会第60号出版物大幅高估了放射性骨癌的风险。这种混淆显然源于对《BEIR IV报告》的错误解读,该报告并未明确区分这两者。还应指出的是,《BEIR IV报告》和《BEIR V报告》中看似骨肉瘤诱发的总结性数值风险估计仅指按224镭计算的平均骨骼剂量。

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