Deng Shan, Yang Xiu-yu
Department of Obstetric and Gynecology, PUMC Hospital, CAMS, PUMC, 100730, China. dengshan39@.hotmail.com
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2002 Aug;24(4):418-21.
In order to get better understanding of placental site trophoblastic tumor (PSTT), we have investigated 4 PSTT cases that diagnosed in our hospital and with literature reviews.
We identified 4 patients of PSTT in our choriocarcinoma ward from Jan, 1985 to Dec, 2000 by retrospective analysis.
PSTT accounted for 3.1@1000 of all trophoblastic diseases, the ratio of PSTT to choriocarcinoma was 1:138. The average age was 31. Two cases were secondary to hydatidiform mole with paremetrial or pulmonary metastasis respectively. All cases received hysterectomy and multiple chemotherapy. With a follow-up of 29 to 84 months, all patients are survived up to now.
PSTT is a rare gestational trophoblastic tumor. Accurate pathological diagnosis is critical for proper treatment. The diagnosis and monitor are rather difficult because the beta-hCG are non-parallel to the growth and disappearance of the tumor. Operation plays an important role in its treatment, and multiple chemotherapy is helpful.
为了更好地了解胎盘部位滋养细胞肿瘤（PSTT），我们对我院诊断的4例PSTT病例进行了研究并复习相关文献。
通过回顾性分析，我们在1985年1月至2000年12月期间从我院绒毛膜癌病房中确定了4例PSTT患者。
PSTT占所有滋养细胞疾病的3.1/1000，PSTT与绒毛膜癌的比例为1:138。平均年龄为31岁。2例分别继发于葡萄胎，伴有宫旁或肺转移。所有病例均接受了子宫切除术和多次化疗。随访29至84个月，所有患者至今存活。
PSTT是一种罕见的妊娠滋养细胞肿瘤。准确的病理诊断对恰当治疗至关重要。由于β-hCG与肿瘤的生长和消退不平行，诊断和监测相当困难。手术在其治疗中起重要作用，多次化疗有帮助。
