Fu Chenwei, Lang Jinghe
Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, CAMS & PUMC, Beijing 100730.
Chin Med Sci J. 2002 Jun;17(2):121-3.
To investigate the serum sE-cadherin level in patients with endometriosis and the alterations of that level in healthy control during the menstrual cycle.
Thirty-two patients with endometriosis and 30 healthy women were tested for serum sE-cadherin levels by enzyme-linked immunosorbent assay.
The serum sE-cadherin levels in healthy control did not vary throughout the menstrual cycle, which were lower than those in patients with endometriosis.
E-cadherin might be involved in endometrial shedding during menstruation in endometriosis patients. The serum sE-cadherin assay might be helpful as a serum marker for the diagnosis and management of endometriosis.
研究子宫内膜异位症患者血清可溶性E-钙黏蛋白（sE-cadherin）水平以及健康对照者在月经周期中该水平的变化。
采用酶联免疫吸附测定法检测32例子宫内膜异位症患者和30名健康女性的血清sE-cadherin水平。
健康对照者的血清sE-cadherin水平在整个月经周期中无变化，且低于子宫内膜异位症患者。
E-钙黏蛋白可能参与子宫内膜异位症患者月经期间的子宫内膜脱落。血清sE-cadherin检测可能有助于作为子宫内膜异位症诊断和管理的血清标志物。
